1. GPCR/G Protein
    Neuronal Signaling
  2. 5-HT Receptor
    Adrenergic Receptor
  3. 5-HT2 antagonist 1

5-HT2 antagonist 1 

Cat. No.: HY-U00365
Handling Instructions

5-HT2 antagonist 1 is a potent antagonist of 5-HT2 receptor, with weak α1 adrenoceptor blocking activity.

For research use only. We do not sell to patients.

5-HT2 antagonist 1 Chemical Structure

5-HT2 antagonist 1 Chemical Structure

CAS No. : 191592-09-3

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Description

5-HT2 antagonist 1 is a potent antagonist of 5-HT2 receptor, with weak α1 adrenoceptor blocking activity.

IC50 & Target

5-HT2 Receptor

 

α1

 

In Vitro

5-HT2 antagonist 1 shows 45%, 88%, 93% inhibition of 10 μM erotonin-induced contraction at 10 nM, 100 nM, 1000 nM, respectively, in guinea pig mesentcric artery. 5-HT2 antagonist 1 causes 1% and 10% inhibition of 10 μM norepinephrine-induced contraction at 10 and 100 nM, respectively, in guinea pig aorta[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

400.49

Formula

C₂₂H₂₉FN₄O₂

CAS No.

191592-09-3

SMILES

O=C1N(CCCN2CCN(C3=CC=C(F)C=C3)CC2)CCC(O)C4=C1C=CN4C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

5-HT2 antagonist 15-HT ReceptorAdrenergic ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorBeta ReceptorInhibitorinhibitorinhibit

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5-HT2 antagonist 1
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HY-U00365
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