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Sugammadex sodium (Synonyms: Org25969)

製品番号: HY-B0079 純度: >98.0%

Sugammadex sodium is a synthetic γ-cyclodextrin derivative, and acts as a new reversal agent for neuromuscular block.


Sugammadex sodium 構造式

Sugammadex sodium 構造式

CAS 番号 : 343306-79-6

容量 価格(税別) 在庫状況 数量
無料サンプル (0.5-1 mg)   今すぐ申し込む  
10 mM * 1 mL in Water USD 91 在庫あり
Estimated Time of Arrival: December 31
10 mg USD 60 在庫あり
Estimated Time of Arrival: December 31
25 mg USD 95 在庫あり
Estimated Time of Arrival: December 31
50 mg USD 132 在庫あり
Estimated Time of Arrival: December 31
100 mg USD 180 在庫あり
Estimated Time of Arrival: December 31
200 mg USD 288 在庫あり
Estimated Time of Arrival: December 31
500 mg USD 540 在庫あり
Estimated Time of Arrival: December 31
1 g   お問い合わせ  
5 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください


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Sugammadex sodium is a synthetic γ-cyclodextrin derivative, and acts as a new reversal agent for neuromuscular block.


Injection of sugammadex has no significant effects on blood pressure or heart rate. After injection of the high rocuronium dose, the 90% recovery of the train-of-four ratio takes 28 min (SD 7 min) after saline, 26 min (SD 9.5 min) after 1 mg/kg sugammadex, and 8 min (SD 3.6 min) after 2.5 mg/kg sugammadex[1]. Sugammadex causes a rapid and complete reversal of rocuronium-induced neuromuscular block. The recovery time to train of four ratio=0.9 after spontaneous recovery is 14.4 min (SD=3.4 min; n=14). This is reduced significantly to 3.7 min (SD=3.3 min; n=4) with sugammadex 0.5 mg/kg and to 1.9 min (SD=1.0 min; n=4) with sugammadex 1.0 mg/kg[2]. The estimated half-life of sugammadex in Rhesus monkey is 30 (SEM=4.9) min[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.





CAS 番号



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Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度

H2O : ≥ 34 mg/mL (15.61 mM)

*"≥" means soluble, but saturation unknown.

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4591 mL 2.2957 mL 4.5913 mL
5 mM 0.0918 mL 0.4591 mL 0.9183 mL
10 mM 0.0459 mL 0.2296 mL 0.4591 mL
*Please refer to the solubility information to select the appropriate solvent.

Female rhesus monkeys with a body weight of 5.2-7.1 kg are sedated with 10 mg/kg ketamine intramuscularly. Two intravenous lines are placed: one for anesthetization, including rocuronium, the other for test drug administration. This is followed by intravenous injection of 25 mg/kg pentobarbitone sodium and a subsequent continuous infusion of 5-10 mg/kg/h. The monkeys are intubated endotracheally, and the lungs are ventilated with a mixture of oxygen and nitrous oxide (volume ratio of 2:3). Four animals are each studied on three different occasions. The occasions differed by the administration of either saline or a low (1.0 mg/kg) or high (2.5 mg/kg) dose of sugammadex. Between the experiments, the monkeys recover for at least 6 weeks. Heart rate and oxygen saturation are determined at the ear with a pulse oximeter. Blood pressure is determined with a cuff placed around the tail. Body temperature is measured by a rectal probe and kept at 37°C-38°C.

MCE はこれらの方法の精度を確認していません。 こちらは参照専用です。


純度: >98.0%

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2


SugammadexOrg25969Org 25969Org-25969OthersInhibitorinhibitorinhibit



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