1. Signaling Pathways
  2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. ADC Linker Inhibitors

ADC Linker Inhibitors

Cleavable

Non-cleavable

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

ADC Linker
Product Name Cleavable Non-cleavable Purity
SPDP
Cleavable
  98.45%
DBCO-NHS ester
Cleavable
  99.00%
MC-Val-Cit-PAB
Cleavable
  99.69%
Val-cit-PAB-OH
Cleavable
  99.64%
Fmoc-Val-Cit-PAB-PNP
Cleavable
  96.13%
Amino-PEG4-alcohol  
Non-cleavable
Sulfo-SMCC sodium  
Non-cleavable
>95.0%
Mc-Val-Cit-PABC-PNP
Cleavable
  98.68%
DBCO-acid
Cleavable
  98.32%
Boc-NH-C6-Br
Cleavable
  >95.0%
SPDB
Cleavable
  99.30%
Fmoc-NH-PEG4-CH2CH2COOH
Cleavable
 
Vipivotide tetraxetan Linker  
Non-cleavable
99.88%
NH2-PEG2-C2-Boc  
Non-cleavable
>98.0%
6-Maleimidohexanoic acid N-hydroxysuccinimide ester  
Non-cleavable
99.96%
Fmoc-Val-Cit-PAB
Cleavable
  98.13%
Hydroxy-PEG4-(CH2)2-Boc  
Non-cleavable
Hydroxy-PEG3-(CH2)2-Boc  
Non-cleavable
>95.0%
N-Boc-diethanolamine
Cleavable
 
Boc-Gly-Gly-Phe-Gly-OH
Cleavable
 
N-Boc-PEG3-bromide
Cleavable
 
BMPS  
Non-cleavable
98.94%
Mal-amido-PEG8-C2-acid  
Non-cleavable
98.07%
Boc-NH-PEG4-CH2CH2NH2
Cleavable
 
Fmoc-NH-PEG1-CH2COOH
Cleavable
 
Succinic anhydride  
Non-cleavable
>98.0%
SPDH
Cleavable
  98.57%
Fmoc-Phe-Lys(Boc)-PAB-PNP
Cleavable
  98.67%
SNPB-sulfo-Me
Cleavable
 
NO2-SPP
Cleavable
 
Cbz-Phe-(Alloc)Lys-PAB-PNP
Cleavable
 
SNPB
Cleavable
 
Gemcitabine-O-Si(di-iso)-O-Mc
Cleavable
 
Amino-PEG4-CH2COOH  
Non-cleavable
PDEC-NB
Cleavable
 
Biotin-PEG2-acid  
Non-cleavable
Fmoc-NH-PEG9-CH2CH2COOH
Cleavable
 
Mal-Phe-C4-Val-Cit-PAB-DMEA
Cleavable
 
Mal-amido-PEG10-C2-​NHS ester  
Non-cleavable
Propargyl-PEG1-SS-PEG1-C2-Boc
Cleavable
 
Propargyl-PEG3-NHS ester
Cleavable
 
Bromo-PEG2-C2-azide  
Non-cleavable
Azido-PEG6-NHS ester
Cleavable
 
Azido-PEG3-Val-Cit-PAB-PNP
Cleavable
 
Azido-PEG6-amine  
Non-cleavable
m-PEG8-Amine
Cleavable
 
Propargyl-PEG2-acid  
Non-cleavable
Mal-amido-PEG5-C2-​NHS ester  
Non-cleavable
Azido-PEG4-Val-Cit-PAB-OH
Cleavable
 
m-PEG11-acid  
Non-cleavable
N-Boc-PEG5-bromide
Cleavable
 
Tr-PEG8-OH  
Non-cleavable
Propargyl-PEG4-thiol  
Non-cleavable
NH-bis-PEG2  
Non-cleavable
THP-PEG6-OH  
Non-cleavable
Mal-Phe-C4-Val-Cit-PAB
Cleavable
 
Fmoc-NH-PEG8-CH2CH2COOH
Cleavable
 
N3-C5-NHS ester  
Non-cleavable
Amino-PEG6-alcohol
Cleavable
 
m-PEG7-Ms
Cleavable
 
Fmoc-Gly-Gly-Phe-OtBu
Cleavable
  99.80%
DBCO-PEG5-NHS ester
Cleavable
 
Bis-PEG1-NHS ester  
Non-cleavable
DBCO-NHCO-PEG4-NHS ester
Cleavable
 
NH-bis(C1-Boc)  
Non-cleavable
m-PEG4-Br
Cleavable
 
Mal-L-PA-NH-Boc  
Non-cleavable
N-Boc-N-bis(PEG4-OH)
Cleavable
 
HDP 30.0643
Cleavable
 
Azido-PEG8-acid  
Non-cleavable
Bis-PEG7-acid
Cleavable
 
Ald-Ph-amido-PEG2-C2-Pfp ester  
Non-cleavable
Fmoc-NH-PEG2-CH2CH2COOH
Cleavable
 
Fmoc-N-methyl-PEG3-CH2CH2COOH
Cleavable
 
Propargyl-O-C1-amido-PEG2-C2-NHS ester  
Non-cleavable
N3-PEG3-C2-PFP ester  
Non-cleavable
NH2-PEG6-Boc  
Non-cleavable
Ald-Ph-amido-PEG1-C2-NHS ester  
Non-cleavable
Sulfo-SNPB
Cleavable
 
Propargyl-PEG8-NH2  
Non-cleavable
PDB-Pfp  
Non-cleavable
TCO-PEG12-NHS ester
Cleavable
 
Propargyl-PEG9-bromide  
Non-cleavable
Fmoc-Ala-Ala-Asn-PABC-PNP
Cleavable
 
Tr-PEG5-OH  
Non-cleavable
Boc-NH-PEG1-CH2CH2COOH
Cleavable
 
Propargyl-PEG5-NHS ester
Cleavable
 
N3-C3-NHS ester  
Non-cleavable
N-Boc-PEG7-alcohol
Cleavable
 
Mal-PEG2-acid  
Non-cleavable
Azido-PEG5-CH2CO2H
Cleavable
 
Amino-PEG3-C2-acid
Cleavable
 
m-PEG7-CH2CH2CHO  
Non-cleavable
Aminooxy-PEG3-azide  
Non-cleavable
m-PEG6-Amine
Cleavable
 
Azido-PEG7-amine  
Non-cleavable
m-PEG4-Boc
Cleavable
 
Ald-Ph-amido-PEG2-C2-NHS ester  
Non-cleavable
m-PEG10-amine  
Non-cleavable
m-PEG4-Ms
Cleavable
 
Mal-​PEG4-​NHS ester  
Non-cleavable
m-PEG3-Amine
Cleavable
 
Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP
Cleavable
 
m-PEG7-Amine
Cleavable
 
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine
Cleavable
 
MAC glucuronide linker-2
Cleavable
 
Amino-PEG2-C2-acid
Cleavable
 
AMAS  
Non-cleavable
MC-PEG2-C2-​NHS ester  
Non-cleavable
Aminooxy-PEG2-alcohol  
Non-cleavable
Fmoc-NH-PEG6-CH2CH2COOH
Cleavable
 
Ald-Ph-amido-PEG2  
Non-cleavable
Propargyl-C1-NHS ester  
Non-cleavable
Propargyl-PEG4-Tos
Cleavable
 
DBCO-PEG4-DBCO
Cleavable
 
MC-Gly-Gly-Phe
Cleavable
  96.57%
Mal-PEG6-NHS ester  
Non-cleavable
N-Boc-PEG6-alcohol
Cleavable
 
Bis-PEG9-NHS ester
Cleavable
 
Boc-NH-PEG4-CH2COOH
Cleavable
 
Ald-CH2-PEG3-azide
Cleavable
 
trans-Sulfo-SMCC  
Non-cleavable
Ald-Ph-amido-PEG4-C2-acid  
Non-cleavable
Mp-polymer ester  
Non-cleavable
Amino-PEG8-Boc
Cleavable
 
DBCO-Maleimide
Cleavable
 
m-PEG3-CH2CH2COOH  
Non-cleavable
m-PEG10-alcohol  
Non-cleavable
Ald-Ph-amido-PEG3-C2-Pfp ester  
Non-cleavable
Propargyl-PEG3-acid  
Non-cleavable
N3-PEG4-C2-Pfp ester  
Non-cleavable
Fmoc-NH-PEG5-CH2COOH
Cleavable
 
Mal-amido-PEG2-NHS ester  
Non-cleavable
6-O-2-Propyn-1-yl-D-galactose  
Non-cleavable
Azide-PEG3-Tos  
Non-cleavable
Aminooxy-PEG2-azide  
Non-cleavable
Ald-Ph-amido-PEG3-C1-Boc  
Non-cleavable
Fmoc-Phe-Lys(Trt)-PAB-PNP
Cleavable
 
N3-C4-NHS ester  
Non-cleavable
TCO-PEG4-NHS ester
Cleavable
 
Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA
Cleavable
 
Sulfo-LC-SPDP
Cleavable
 
Ald-Ph-NHS ester  
Non-cleavable
Azido-PEG8-NHS ester
Cleavable
 
Azido-PEG6-alcohol  
Non-cleavable
Bis-PEG5-NHS ester
Cleavable
 
N-Boc-PEG4-bromide
Cleavable
 
m-PEG5-Ms
Cleavable
 
Boc-Gly-Gly-Phe-Gly-OH TFA
Cleavable
  98.27%
Amino-PEG11-OH
Cleavable
 
Boc-Phe-(Alloc)Lys-PAB-PNP
Cleavable
 
Bis-PEG9-acid
Cleavable
 
Mal-amido-(CH2COOH)2
Cleavable
 
m-PEG11-Amine
Cleavable
 
Hydroxy-PEG4-acid
Cleavable
 
m-PEG4-Amine
Cleavable
 
Azido-PEG5-acid  
Non-cleavable
Mal-PEG4-VC-PAB-DMEA
Cleavable
 
PEG4-SPDP
Cleavable
 
Azido-PEG5-alcohol  
Non-cleavable
m-PEG12-OH  
Non-cleavable
DBCO-NHS ester 3
Cleavable
 
Mal-PEG2-VCP-NB  
Non-cleavable
95.38%
N-Boc-PEG2-bromide
Cleavable
 
Bis-PEG1-PFP ester  
Non-cleavable
NO2-SPP-sulfo-Me
Cleavable
 
Bis-PEG13-NHS ester
Cleavable
 
Fmoc-NH-PEG6-CH2COOH
Cleavable
 
Propargyl-PEG7-NHS ester
Cleavable
 
Propargyl-PEG4-Br  
Non-cleavable
Mal-PEG2-Val-Cit-amido-PAB-OH
Cleavable
 
Azido-PEG4-CH2-Boc
Cleavable
 
Azido-PEG9-acid  
Non-cleavable
DSP Crosslinker
Cleavable
 
PDP-C1-Ph-Val-Cit
Cleavable
 
CL2 Linker
Cleavable
 
Propargyl-C2-NHS ester  
Non-cleavable
NHPI-PEG2-C2-Pfp ester  
Non-cleavable
NH2-PEG9-acid  
Non-cleavable
N-Boc-N-bis(PEG2-OH)
Cleavable
 
EC089
Cleavable
 
Propargyl-PEG1-NHS ester  
Non-cleavable
Aminoethyl-SS-ethylalcohol
Cleavable
 
Propargyl-PEG4-C2-acid  
Non-cleavable
Fmoc-PEA
Cleavable
 
MAC glucuronide linker-1  
Non-cleavable
95.91%
m-PEG12-amine  
Non-cleavable
Sulfo-SPP
Cleavable
 
Br-PEG4-C2-Boc
Cleavable
 
Propargyl-PEG2-NHBoc
Cleavable
 
Mal-C2-Gly3-EDA
Cleavable
 
N3-PEG2-C2-PFP ester  
Non-cleavable
Ald-Ph-amido-PEG3-C-COOH  
Non-cleavable
Amino-Tri-(carboxyethoxymethyl)-methane
Cleavable
 
m-PEG2-Amine
Cleavable
 
PDdB-Pfp  
Non-cleavable
Fmoc-Asp-NH2
Cleavable
 
Mal-PEG3-NHS ester  
Non-cleavable
N3-Ph-NHS ester  
Non-cleavable
m-PEG5-CH2COOH  
Non-cleavable
HDP 30.1465
Cleavable
 
Ald-Ph-amido-PEG1-C2-Pfp ester  
Non-cleavable
DBCO-NHCO-PEG4-NH-Boc
Cleavable
 
4-N3Pfp-NHS ester  
Non-cleavable
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate
Cleavable
 
Fmoc-NH-PEG8-CH2COOH
Cleavable
 
HDP 30.0880
Cleavable
 
Bis-​PEG2-​NHS ester  
Non-cleavable
N3-C2-NHS ester  
Non-cleavable
BnO-PEG6-OH  
Non-cleavable
NH2-PEG5-OH  
Non-cleavable
m-PEG6-CH2CH2CHO  
Non-cleavable
DBCO-Sulfo-NHS ester sodium
Cleavable
 
Propargyl-PEG5-amine  
Non-cleavable
Aminooxy-PEG4-alcohol  
Non-cleavable
DBCO-Sulfo-Link-biotin
Cleavable
 
PEG12-Tos  
Non-cleavable
Ala-Ala-Asn-PAB
Cleavable
 
Azido-PEG3-maleimide
Cleavable
 
DBCO-(PEG2-Val-Cit-PAB)2
Cleavable
 
DBCO-NHCO-PEG4-amine
Cleavable
 
DMAC-PDB
Cleavable
 
Bis-PEG8-acid
Cleavable
 
NHPI-PEG2-C2-NHS ester  
Non-cleavable
Bis-PEG21-NHS ester
Cleavable
 
TCO-PEG4-DBCO
Cleavable
 
Propargyl-PEG8-bromide  
Non-cleavable
Phe-Lys(Fmoc)-PAB
Cleavable
 
SPDV
Cleavable
 
DBCO-PEG4-amine
Cleavable
 
N3-PEG3-CH2CH2-Boc
Cleavable
 
m-PEG10-acid  
Non-cleavable
m-PEG2-Tos  
Non-cleavable
Amino-PEG9-acid  
Non-cleavable
Azido-PEG9-amine  
Non-cleavable
Mal-PEG4-Val-Cit-PAB
Cleavable
 
DBCO-PEG4-Maleimide
Cleavable
 
LC-PEG8-SPDP
Cleavable
 
m-PEG6-NHS ester  
Non-cleavable
Azido-PEG2-C2-amine  
Non-cleavable
Mc-Leu-Gly-Arg
Cleavable
 
Maleimido-tri(ethylene glycol)-propionic acid
Cleavable
 
Sulfo-SIAB  
Non-cleavable
Propargyl-O-C1-amido-PEG4-C2-NHS ester  
Non-cleavable
Propargyl-PEG8-acid
Cleavable
 
Propargyl-PEG6-NHS ester
Cleavable
 
Mal-PEG1-NHS ester
Cleavable
 
m-PEG5-succinimidyl carbonate  
Non-cleavable
Ald-Ph-amido-C2-nitrate  
Non-cleavable
N3-PEG3-C2-NHS ester  
Non-cleavable
Bis-PEG2-PFP ester  
Non-cleavable
Propargyl-PEG4-NHS ester  
Non-cleavable
Ald-Ph-amido-PEG4-C2-NHS ester  
Non-cleavable
Fmoc-Gly-Gly-D-Phe-OtBu
Cleavable
  98.28%
Mc-Val-Cit-PAB-Cl
Cleavable
 
Fmoc-NH-PEG3-CH2CH2COOH
Cleavable
 
Fmoc-NH-PEG4-CH2COOH
Cleavable
 
Sulfo-SIAB sodium  
Non-cleavable
m-PEG9-Amine
Cleavable
 
N3-PEG2-C2-NHS ester  
Non-cleavable
Mal-PEG4-VA  
Non-cleavable
Bis-PEG17-NHS ester
Cleavable
 
Propargyl-PEG7-acid
Cleavable
 
Phe-Lys(Trt)-PAB
Cleavable
 
Bis-PEG25-NHS ester
Cleavable
 
NH2-PEG6-CH2CH2COOH
Cleavable
 
DBCO-amine
Cleavable
 
NHPI-PEG3-C2-Pfp ester  
Non-cleavable
Propargyl-PEG4-CH2CH2-Boc  
Non-cleavable
Tetraethylene glycol monotosylate
Cleavable
 
Propargyl-PEG2-amine  
Non-cleavable
DBCO-​C6-​acid  
Non-cleavable
N-Butanoyl-L-homoserine lactone
Cleavable
 
SPP
Cleavable
 
N-Boc-PEG9-alcohol
Cleavable
 
N3-PEG3-CH2CH2COOH  
Non-cleavable
DSG Crosslinker
Cleavable
 
SC-Val-Cit-PAB
Cleavable
 
Mal-PEG4-PFP ester  
Non-cleavable
Boc-NH-PEG6-CH2CH2COOH
Cleavable
 
Mal-C2-NHS ester  
Non-cleavable
NHPI-PEG3-C2-NHS ester  
Non-cleavable
Propargyl-PEG8-NHS ester
Cleavable
 
Mal-PEG1-acid  
Non-cleavable
Bis-PEG7-NHS ester
Cleavable
 
m-PEG7-CH2COOH  
Non-cleavable
Boc-Val-Cit-OH
Cleavable
 
Propargyl-PEG6-acid
Cleavable
 
Mal-PEG2-NHS ester  
Non-cleavable
Hydroxy-PEG2-(CH2)2-Boc  
Non-cleavable
Bis-PEG3-NHS ester  
Non-cleavable
Amino-PEG5-C2-acid  
Non-cleavable
CL2A
Cleavable
 
Hydroxy-PEG3-SS-PEG3-alcohol
Cleavable
 
N3-PEG4-C2-NHS ester  
Non-cleavable
DBCO-NHCO-PEG4-acid
Cleavable
 
Amino-PEG10-OH
Cleavable
 
Bis-​PEG4-​NHS ester  
Non-cleavable
NH2-PEG4-CH2CH2COOH
Cleavable
 
Bis-PEG10-NHS ester
Cleavable
 
m-PEG8-Ms
Cleavable
 
PDdEC-NB
Cleavable
 
Bis-PEG6-NHS ester
Cleavable
 
(Ac)Phe-Lys(Alloc)-PABC-PNP
Cleavable