1. Signaling Pathways
  2. PI3K/Akt/mTOR
  3. Akt
  4. Akt Inhibitors

Akt Inhibitors

Akt

Akt1

Akt2

Akt3

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Akt Inhibitors, Activators & Modulators
Product Name Akt Akt1 Akt2 Akt3 Purity
MK-2206 dihydrochloride  
Akt1, IC50: 5 nM
Akt2, IC50: 12 nM
Akt3, IC50: 65 nM
99.69%
SC79
Akt
      >98.0%
Honokiol
Akt
      99.90%
Capivasertib  
Akt1, IC50: 3 nM
Akt2, IC50: 7 nM
Akt3, IC50: 7 nM
99.71%
Ipatasertib  
Akt1, IC50: 5 nM
Akt2, IC50: 18 nM
Akt3, IC50: 8 nM
98.42%
Sophocarpine (monohydrate)
Akt
      >99.0%
Sophocarpine
Akt
      >98.0%
AKT inhibitor VIII  
Akt1, IC50: 58 nM
Akt2, IC50: 210 nM
Akt3, IC50: 2119 nM
98.02%
GSK-690693  
Akt1, IC50: 2 nM
Akt2, IC50: 13 nM
Akt3, IC50: 9 nM
99.22%
Oridonin  
Akt1, IC50: 8.4 μM
Akt2, IC50: 8.9 μM
  99.85%
Uprosertib  
Akt1, IC50: 180 nM
Akt2, IC50: 328 nM
Akt3, IC50: 38 nM
99.85%
Artemisinin
pAKT
      >98.0%
Scutellarin
Akt
      >98.0%
Perifosine
Akt
      >98.0%
LM22B-10
Akt
      98.81%
Afuresertib  
Akt1 E17K mutant, IC50: 0.2 nM
Akt2, Ki: 2 nM
Akt3, Ki: 2.6 nM
98.95%
1,3-Dicaffeoylquinic acid
Akt
      99.82%
Triciribine
Akt, IC50: 130 nM (Cell Assay)
      99.20%
Miltefosine
Akt
      >98.0%
Deguelin
Akt
      99.56%
Miransertib  
Akt1, IC50: 2.7 nM
Akt2, IC50: 14 nM
Akt3, IC50: 8.1 nM
99.77%
AT7867  
Akt1, IC50: 32 nM
Akt2, IC50: 17 nM
Akt3, IC50: 47 nM
98.68%
A-674563 hydrochloride  
Akt1, Ki: 11 nM
    99.78%
CCT128930    
Akt2, IC50: 6 nM
  99.15%
BAY1125976  
Akt1, IC50: 5.2 nM (at 10 μM ATP)
Akt2, IC50: 18 nM (at 10 μM ATP)
Akt3, IC50: 427 nM (at 10 μM ATP)
99.86%
Ipatasertib dihydrochloride  
Akt1, IC50: 5 nM
Akt2, IC50: 18 nM
Akt3, IC50: 8 nM
99.59%
AT13148  
Akt1, IC50: 38 nM
Akt2, IC50: 402 nM
Akt3, IC50: 50 nM
99.54%
PHT-427
Akt, Ki: 2.7 μM
      99.56%
AKT Kinase Inhibitor
Akt
      98.37%
Afuresertib hydrochloride  
Akt1, Ki: 0.08 nM
Akt1 E17K mutant, IC50: 0.2 nM
Akt2, Ki: 2 nM
Akt3, Ki: 2.6 nM
98.02%
PF-AKT400  
PKBα, IC50: 0.5 nM
    95.75%
Guggulsterone
Akt
      99.50%
Pachymic acid
Akt
      >99.0%
Akt1 and Akt2-IN-1  
Akt1, IC50: 3.5 nM
Akt2, IC50: 42 nM
  99.71%
Cenisertib
Akt
      99.56%
SC66
Akt
      99.32%
Borussertib
Aktwt, IC50: 0.8 nM
Aktwt, Ki: 2.2 nM
      98.19%
Deltonin
Akt
      99.93%
Recilisib
Akt
      >98.0%
Loureirin A
Akt
      99.76%
Polygalasaponin F
Akt
     
Crosstide
Akt
      98.35%
Theaflavin 3,3'-digallate
Akt
      98.70%
N-Oleoyl glycine
Akt
      >99.0%
AT7867 dihydrochloride  
Akt1, IC50: 32 nM
Akt2, IC50: 17 nM
Akt3, IC50: 47 nM
99.77%
3CAI  
Akt1
Akt2
  99.66%
CHPG sodium salt
Akt
     
AKT-IN-3  
Akt1, IC50: 1.4 nM
Akt2, IC50: 1.2 nM
Akt3, IC50: 1.7 nM
MPT0E028
Akt
     
CHPG
Akt
     
AKT-IN-2  
Akt1, IC50: 5 nM
   
INY-03-041  
Akt1, IC50: 2.0 nM
Akt2, IC50: 6.8 nM
Akt3, IC50: 3.5 nM
Hematein
Akt
     
Phellodendrine
Akt
     
Hederacolchiside A1
Akt
     
Rotundic acid
Akt
     
Esculetin
Akt
     
Paris saponin VII
Akt
     
(Z)-Guggulsterone
Akt
     
Arnicolide D
Akt
     
Glaucocalyxin A
Akt
     
K-80003
Akt
     
Uprosertib hydrochloride  
Akt1, IC50: 180 nM
Akt2, IC50: 328 nM
Akt3, IC50: 38 nM