1. Signaling Pathways
  2. PI3K/Akt/mTOR
  3. Akt
  4. Akt Inhibitors

Akt Inhibitors

Akt

Akt1

Akt2

Akt3

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Akt Inhibitors, Activators & Modulators
Product Name Akt Akt1 Akt2 Akt3 Purity
MK-2206 dihydrochloride  
Akt1, IC50: 8 nM
Akt2, IC50: 12 nM
Akt3, IC50: 65 nM
99.76%
SC79
Akt
      ≥98.0%
Capivasertib  
Akt1, IC50: 3 nM
Akt2, IC50: 7 nM
Akt3, IC50: 7 nM
≥98.0%
Honokiol
Akt
      99.90%
Ipatasertib  
Akt1, IC50: 5 nM
Akt2, IC50: 18 nM
Akt3, IC50: 8 nM
≥98.0%
A-674563  
Akt1, Ki: 11 nM
    ≥95.0%
MK-2206  
Akt1, : 8 nM
Akt2, : 12 nM
Akt3, : 65 nM
AKT inhibitor VIII  
Akt1, IC50: 58 nM
Akt2, IC50: 210 nM
Akt3, IC50: 2119 nM
98.93%
GSK-690693  
Akt1, IC50: 2 nM
Akt2, IC50: 13 nM
Akt3, IC50: 9 nM
99.22%
Artemisinin
pAKT
      ≥98.0%
Perifosine
Akt
      ≥98.0%
Oridonin  
Akt1, IC50: 8.4 μM
Akt2, IC50: 8.9 μM
  99.85%
Guggulsterone
Akt
      99.81%
Miransertib  
Akt1, IC50: 2.7 nM
Akt2, IC50: 14 nM
Akt3, IC50: 8.1 nM
99.77%
Uprosertib  
Akt1, IC50: 180 nM
Akt2, IC50: 328 nM
Akt3, IC50: 38 nM
98.93%
Triciribine
Akt, IC50: 130 nM (Cell Assay)
      99.81%
A-443654  
Akt1, Ki: 160 pM
Akt2, Ki: 160 pM
Akt3, Ki: 160 pM
99.04%
Afuresertib  
Akt1 E17K mutant, IC50: 0.2 nM
Akt2, Ki: 2 nM
Akt3, Ki: 2.6 nM
99.86%
Scutellarin
Akt
      ≥98.0%
Deguelin
Akt
      ≥98.0%
Recilisib
Akt
      ≥98.0%
Miltefosine
Akt
      ≥98.0%
Ipatasertib dihydrochloride  
Akt1, IC50: 5 nM
Akt2, IC50: 18 nM
Akt3, IC50: 8 nM
99.27%
A-674563 hydrochloride  
Akt1, Ki: 11 nM
    99.86%
CCT128930    
Akt2, IC50: 6 nM
  99.53%
LM22B-10
Akt
      98.60%
α-Linolenic acid
Akt
      ≥99.0%
AT13148  
Akt1, IC50: 38 nM
Akt2, IC50: 402 nM
Akt3, IC50: 50 nM
≥98.0%
Afuresertib hydrochloride  
Akt1, Ki: 0.08 nM
Akt1 E17K mutant, IC50: 0.2 nM
Akt2, Ki: 2 nM
Akt3, Ki: 2.6 nM
98.02%
Pachymic acid
Akt
      ≥99.0%
AT7867  
Akt1, IC50: 32 nM
Akt2, IC50: 17 nM
Akt3, IC50: 47 nM
≥95.0%
BAY1125976  
Akt1, IC50: 5.2 nM (at 10 μM ATP)
Akt2, IC50: 18 nM (at 10 μM ATP)
Akt3, IC50: 427 nM (at 10 μM ATP)
99.86%
Cenisertib
Akt
      99.56%
1,3-Dicaffeoylquinic acid
Akt
      98.85%
3CAI  
Akt1
Akt2
  99.66%
AKT Kinase Inhibitor
Akt
      98.37%
SC66
Akt
      99.88%
M2698  
Akt1, IC50: 1 nM
 
Akt3, IC50: 1 nM
≥99.0%
PHT-427
Akt, Ki: 2.7 μM
      99.56%
Akt1 and Akt2-IN-1  
Akt1, IC50: 3.5 nM
Akt2, IC50: 42 nM
  99.17%
Esculetin
Akt
      ≥98.0%
Sophocarpine
Akt
      ≥98.0%
N-Oleoyl glycine
Akt
      ≥99.0%
Borussertib
Aktwt, IC50: 0.8 nM
Aktwt, Ki: 2.2 nM
      98.59%
PF-AKT400  
PKBα, IC50: 0.5 nM
    95.75%
KP372-1
Akt
      99.52%
Phellodendrine
Akt
      99.37%
Loureirin A
Akt
      99.92%
Arnicolide D
Akt
      ≥99.0%
CHPG
Akt
      ≥99.0%
Deltonin
Akt
      ≥99.0%
Paris saponin VII
Akt
      ≥99.0%
(Z)-Guggulsterone
Akt
      98.27%
Polygalasaponin F
Akt
      ≥99.0%
Crosstide
Akt
      98.35%
Glaucocalyxin A
Akt
      99.38%
Hematein
Akt
     
Hederacolchiside A1
Akt
      ≥99.0%
N-​Feruloyloctopamine
Akt
      98.49%
K-80003
Akt
      98.02%
AT7867 dihydrochloride  
Akt1, IC50: 32 nM
Akt2, IC50: 17 nM
Akt3, IC50: 47 nM
99.17%
Sophocarpine monohydrate
Akt
      ≥99.0%
Rotundic acid
Akt
      ≥99.0%
DB07107  
Akt1, IC50: 360 nM
   
Sennidin B
Akt
      98.15%
CAY10404
Akt
      ≥99.0%
Miransertib hydrochloride  
Akt1, IC50: 2.7 nM
Akt2, IC50: 174 nM
Akt3, IC50: 8.1 nM
CHPG sodium salt
Akt
     
AKT-IN-3  
Akt1, IC50: 1.4 nM
Akt2, IC50: 1.2 nM
Akt3, IC50: 1.7 nM
MPT0E028
Akt
     
AKT-IN-2  
Akt1, IC50: 5 nM
   
AKTide-2T TFA
Akt
     
Sennidin A
Akt
     
AKTide-2T
Akt
     
Uprosertib hydrochloride  
Akt1, IC50: 180 nM
Akt2, IC50: 328 nM
Akt3, IC50: 38 nM