1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. Aurora Kinase
  4. Aurora Kinase Inhibitors

Aurora Kinase Inhibitors

Aurora A

Aurora B

Aurora C

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Aurora Kinase Inhibitors
Product Name Aurora A Aurora B Aurora C Purity
Alisertib
Aurora A, IC50: 1.2 nM
Aurora B, IC50: 396.5 nM
  ≥95.0%
Barasertib-HQPA  
Aurora B, IC50: 0.37 nM
  99.47%
Tozasertib
Aurora A, Ki: 0.6 nM
Aurora B, Ki: 18 nM
Aurora C, Ki: 4.6 nM
99.94%
MK-5108
Aurora A, IC50: 64 pM
    ≥98.0%
LY3295668
Aurora A, IC50: 0.8 nM
    98.36%
Chiauranib  
Aurora B, IC50: 9 nM
  99.28%
CD532
Aurora A, IC50: 45 nM
   
Barasertib  
Aurora B, IC50: 0.37 nM
  99.62%
AT9283
Aurora A, IC50: 3 nM
Aurora B, IC50: 3 nM
  99.61%
PF-03814735
Aurora 1, IC50: 0.8 nM
Aurora 2, IC50: 5 nM
  99.82%
Danusertib
Aurora A, IC50: 13 nM
Aurora B, IC50: 79 nM
Aurora C, IC50: 61 nM
≥98.0%
Reversine
Aurora A, IC50: 400 nM
Aurora B, IC50: 500 nM
Aurora C, IC50: 400 nM
99.40%
JNJ-7706621
Aurora A, IC50: 11 nM
Aurora B, IC50: 15 nM
  99.96%
ZM-447439
Aurora A, IC50: 110 nM
Aurora B, IC50: 130 nM
  99.19%
GSK-1070916  
Aurora B, Ki: 0.38 nM
Aurora C, Ki: 1.5 nM
99.55%
MLN8054
Aurora A, IC50: 4 nM
    ≥98.0%
KW-2449
Aurora A, IC50: 48 nM
    99.85%
SNS-314 mesylate
Aurora A, IC50: 9 nM
Aurora B, IC50: 31 nM
Aurora C, IC50: 6 nM
99.90%
ENMD-2076
Aurora A, IC50: 14 nM
    99.12%
Hesperadin  
Aurora B, IC50: 250 nM
  ≥98.0%
AMG 900
Aurora A, IC50: 5 nM
Aurora B, IC50: 4 nM
Aurora C, IC50: 1 nM
99.29%
CYC-116
Aurora A, Ki: 8 nM
Aurora B, Ki: 9.2 nM
  ≥98.0%
XL228
Aurora A, IC50: 3.1 nM
    99.58%
MK-8745
Aurora A, IC50: 0.6 nM
    99.28%
Cenisertib
Aurora-A
Aurora-B
  99.56%
TCS7010
Aurora A, IC50: 3.4 nM
Aurora B, IC50: 3.4 μM
  99.22%
PHA-680632
Aurora A, IC50: 27 nM
Aurora B, IC50: 135 nM
Aurora C, IC50: 120 nM
98.48%
Ilorasertib hydrochloride
Aurora A, IC50: 120 nM
Aurora B, IC50: 7 nM
Aurora B (Y156H), IC50: 12 nM
Aurora C, IC50: 1 nM
98.91%
SCH-1473759 hydrochloride
Aurora A, IC50: 4 nM
Aurora B, IC50: 13 nM
  99.79%
PF 477736
Aurora-A, IC50: 23 nM
    99.21%
BI-847325    
Aurora C, IC50: 15 nM
99.14%
CCT 137690
Aurora A, IC50: 15 nM
Aurora B, IC50: 25 nM
Aurora C, IC50: 19 nM
99.10%
TAK-901
Aurora A, IC50: 21 nM
Aurora B, IC50: 15 nM
  ≥98.0%
Aurora kinase inhibitor-3
Aurora A, IC50: 42 nM
    99.34%
CCT129202
Aurora A, IC50: 42 nM
Aurora B, IC50: 198 nM
Aurora C, IC50: 227 nM
98.24%
NU6140
Aurora A, IC50: 67 nM
Aurora B, IC50: 35 nM
  ≥99.0%
ENMD-2076 Tartrate
Aurora A, IC50: 1.86 nM
    98.87%
TAS-119
Aurora A, IC50: 1 nM
Aurora B, IC50: 95 nM
  98.27%
SCH-1473759
Aurora A, IC50: 4 nM
Aurora B, IC50: 13 nM
  98.20%
SP-96
Aurora A, IC50: 18.975 nM
Aurora B, IC50: 0.316 nM
  98.03%
GW779439X
Aurora A
   
JB170
Aurora A, DC50: 28 nM
Aurora A, Kd: 99 nM
Aurora A, EC50: 193 nM
   
AKI603
Aurora A, IC50: 12.3 nM
    98.05%
Ilorasertib
Aurora A, IC50: 120 nM
Aurora B, IC50: 7 nM
Aurora B (Y156H), IC50: 12 nM
Aurora C, IC50: 1 nM
≥98.0%
Alisertib sodium
Aurora A, IC50: 12.5 nM
Aurora B, IC50: 396.5 nM
 
Hesperadin hydrochloride  
Aurora B, IC50: 250 nM
 
Aurora inhibitor 1
Aurora A, IC50: 4 nM
Aurora B, IC50: 13 nM
 
TC-A 2317 hydrochloride
Aurora A, Ki: 1.2 nM
Aurora B, Ki: 101 nM
 
Glycyl H-1152 hydrochloride
Aurora A, IC50: 2.35 μM
   
Aurora kinase inhibitor-2
Aurora A, IC50: 310 nM
Aurora B, IC50: 240 nM
  99.19%
Aurora B inhibitor 1  
Aurora B, Ki: 0.01 μM