1. Signaling Pathways
  2. GPCR/G Protein
    Immunology/Inflammation
  3. CCR
  4. CCR Inhibitors

CCR Inhibitors

CCR1

CCR2

CCR3

CCR4

CCR5

CCR6

CCR7

CCR8

CCR9

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

CCR Inhibitors, Agonists & Antagonists
Product Name CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 Purity
Maraviroc        
MIP-1α-CCR5, IC50: 3.3 nM (in HEK-293 cell membrane)
MIP-1β-CCR5, IC50: 7.2 nM (in HEK-293 cell membrane)
RANTES-CCR5, IC50: 5.2 nM (in HEK-293 cell membrane)
        99.95%
RS 504393  
CCR2, IC50: 89 nM
              99.75%
INCB3344  
hCCR2, IC50: 5.1 nM
mCCR2, IC50: 9.5 nM
              99.73%
PF-4136309  
Human CCR2, IC50: 5.2 nM
Mouse CCR2, IC50: 13 nM
Rat CCR2, IC50: 17 nM
              ≥98.0%
Aplaviroc hydrochloride        
CCR5
        98.84%
Nifeviroc        
CCR5
       
Cenicriviroc  
CCR2, IC50: 5.9 nM
   
CCR5, IC50: 0.29 nM
        98.07%
BX471
MIP-1α-CCR1, Ki: 1 nM
RANTES-CCR1, Ki: 2.8 nM
MCP-3-CCR1, Ki: 5.5 nM
                99.78%
TAK-779  
MCP-1-CCR2b, IC50: 27 nM (in CHO/CCR5 cells)
   
MIP-1β-CCR5, IC50: 1 nM (in CHO/CCR5 cells)
RANTES-CCR5, IC50: 1.4 nM (in CHO/CCR5 cells)
MIP-1α-CCR5, IC50: 1 nM (in CHO/CCR5 cells)
        ≥98.0%
RS102895 hydrochloride
CCR1, IC50: 17800 nM
CCR2, IC50: 360 nM
              99.69%
Cenicriviroc Mesylate  
CCR2, IC50: 5.9 nM
   
CCR5, IC50: 0.29 nM
        98.84%
AZ084              
CCR8, Ki: 0.9 nM
  99.36%
CCR6 inhibitor 1          
Moneky CCR6, IC50: 0.45 nM
Human CCR6, IC50: 6 nM
Human CCR7, IC50: 9400 nM
    99.82%
BMS-813160  
CCR2
   
CCR5
        99.89%
Vercirnon                
CCR9, IC50: 10 nM
98.19%
BX471 hydrochloride
MIP-1α-CCR1, Ki: 1 nM
RANTES-CCR1, Ki: 2.8 nM
MCP-3-CCR1, Ki: 5.5 nM
                98.0%
MK-0812 Succinate  
CCR2
              99.69%
AZD2098      
CCR4
          99.86%
CCR2-RA-[R]  
CCR2, IC50: 103 nM (in U2OS-CCR2 cells)
              98.41%
INCB 3284  
MCP-1-hCCR2, IC50: 3.7 nM
              ≥98.0%
GW 766994    
CCR3, pKi: 7.86
            99.53%
CCR2 antagonist 4 hydrochloride  
CCR2b, IC50: 180 nM
              99.88%
CCR7 Ligand 1            
Human CCR7, Kd: 3 nM
    99.64%
J-113863
CCR1, IC50: 0.9 nM (Human CCR1)
CCR1, IC50: 5.8 nM (Mouse CCR1)
 
CCR3, IC50: 0.58 nM (Human CCR3)
CCR3, IC50: 460 nM (Mouse CCR3)
            ≥99.0%
TAK-220        
RANTES-CCR5, IC50: 3.5 nM (in CHO cells)
MIP-1α-CCR5, IC50: 1.4 nM (in CHO cells)
        99.95%
Vicriviroc maleate        
CCR5, Ki: 2.5 nM
        99.91%
DAPTA        
gp120BaL/sCD4-CCR5, IC50: 55 pM (in Cf2Th/synR5 cells)
gp120CMCM235/sCD4-CCR5, IC50: 0.32 nM (in Cf2Th/synR5 cells)
        95.16%
LMD-009              
CCR8, EC50: 11-87 nM
  99.85%
C-021 dihydrochloride      
CCR4
          ≥99.0%
ZK756326 dihydrochloride              
CCR8, IC50: 1.8 μM (in U87 cells)
  98.28%
GSK2239633A      
[125I]-TARC-CCR4, pIC50: 7.96
          99.77%
Vercirnon sodium                
CCR9, IC50: 10 nM
98.76%
AZD2423  
CCR2
              98.56%
CCR2 antagonist 4  
CCR2b, IC50: 180 nM
              ≥99.0%
BMS CCR2 22  
CCR2, IC50: 5.1 nM
              ≥99.0%
CCR1 antagonist 8
CCR1, IC50: 1.8 nM (in Ca2+ flux assay)
                99.54%
CCR2 antagonist 3  
CCR2
              98.10%
R243              
CCR8
  98.90%
CCR1 antagonist 9
CCR1, IC50: 6.8 nM (in calcium flux assay)
                99.88%
PF-04634817  
Rat CCR2, IC50: 20.8 nM
   
CCR5, IC50: 470 nM
        98.87%
YM022
CCR1, Ki: 63 nM
CCR2, Ki: 68 pM
              ≥99.0%
CCR2 antagonist 1  
CCR2, Ki: 2.4 nM
              98.67%
Aplaviroc        
CCR5
       
CCX354
CCR1
                ≥99.0%
RS102895
CCR1, IC50: 17800 nM
CCR2, IC50: 360 nM
             
MK-0812  
CCR2
              99.75%
INCB 3284 dimesylate  
MCP-1-hCCR2, IC50: 3.7 nM
              ≥98.0%
ALK4290    
CCR3, Ki: 3.2 nM
           
CCR4 antagonist 3      
CCR4
         
PF-04634817 succinate  
Rat CCR2, IC50: 20.8 nM
   
CCR5, IC50: 470 nM
        ≥99.0%
CCR5 antagonist 1        
CCR5
       
CCR3 antagonist 1    
CCR3