2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. CDK
  5. CDK6 Isoform
  6. CDK6 Degrader

CDK6 Degrader

CDK6 Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-148530
    YX-2-107
    		Degrader 99.79%
    YX-2-107 is a PROTAC (IC50= 4.4 nM) that selectively degrades CDK6. YX-2-107 effectively inhibits RB phosphorylation and FOXM1 expression in vitro and inhibits the development of Ph+ ALL in rats. YX-2-107 can be used in the study of Ph chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL).