1. Signaling Pathways
  2. Epigenetics
  3. DNA Methyltransferase
  4. DNA Methyltransferase Inhibitors

DNA Methyltransferase Inhibitors

DNA Methyltransferase

DNMT1

DNMT3

MGMT

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

DNA Methyltransferase Inhibitors
Product Name DNA Methyltransferase DNMT1 DNMT3 MGMT Purity
Decitabine  
DNMT1
DNMT3A
DNMT3B
  99.99%
5-Azacytidine  
DNMT1
    99.97%
SGI-1027  
DNMT1, IC50: 12.5 μM
DNMT3B, IC50: 7.5 μM
DNMT3A, IC50: 8 μM
  99.92%
Guadecitabine sodium  
DNMT1
    98.06%
RG108  
CpG methylase M.SssI, IC50: 115 nM
    99.81%
Zebularine  
DNMT1
DNMT3a/3L
  99.92%
Lomeguatrib      
MGMT, IC50: 9 nM
MGMT, IC50: 6 nM (in MCF-7 cells)
98.53%
Hinokitiol  
DNMT1
    99.28%
Guadecitabine
DNA Methyltransferase
      98.00%
CM-579 trihydrochloride
DNA Methyltransferase, IC50: 32 nM
DNMT1, Kd: 1.5 nM
DNMT3A, IC50: 92 nM
DNMT3B, IC50: 1000 nM
  98.03%
γ-Oryzanol  
DNMT1, IC50: 3.2 μM
DNMT3A, IC50: 22.3 μM
  >95.0%
DC_517  
DNMT1, Kd: 0.91 μM
DNMT1, IC50: 1.7 μM
    99.66%
DC-05  
DNMT1, Kd: 1.09 μM
DNMT1, IC50: 10.3 μM
    99.15%
CM-579
DNA Methyltransferase, IC50: 32 nM
DNMT1, Kd: 1.5 nM
DNMT3A, IC50: 92 nM
DNMT3B, IC50: 1000 nM
 
O6BTG-octylglucoside      
MGMT, IC50: 32 nM
>95.0%