1. Signaling Pathways
  2. PI3K/Akt/mTOR
    Stem Cell/Wnt
  3. GSK-3
  4. GSK-3 Inhibitors

GSK-3 Inhibitors

GSK-3

GSK-3α

GSK-3β

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

GSK-3 Inhibitors
Product Name GSK-3 GSK-3α GSK-3β Purity
CHIR-99021  
GSK-3α, IC50: 10 nM
GSK-3β, IC50: 6.7 nM
≥98.0%
SB 216763  
GSK-3α, IC50: 34.3 nM
GSK-3β, IC50: 34.3 nM
99.30%
LY2090314  
GSK-3α, IC50: 1.5 nM
GSK-3β, IC50: 0.9 nM
99.01%
Tideglusib    
GSK-3β(WT), IC50: 5 nM
GSK-3β(C199A), IC50: 60 nM
99.66%
TWS119    
GSK-3β, IC50: 30 nM
≥98.0%
Manzamine A hydrochloride    
GSK-3β, IC50: 10.2 μM
99.29%
AR-A014418    
GSK-3β, IC50: 104 nM
99.49%
TDZD-8    
GSK-3β, IC50: 2 μM
99.76%
CHIR-99021 monohydrochloride  
GSK-3α, IC50: 10 nM
GSK-3β, IC50: 6.7 nM
99.93%
Kenpaullone    
GSK-3β, IC50: 0.023 μM
≥97.0%
GSK 3 Inhibitor IX  
GSK-3α, IC50: 5 nM
GSK-3β, IC50: 5 nM
≥98.0%
Cromolyn sodium    
GSK-3β, IC50: 2 μM
99.10%
CHIR-99021 trihydrochloride  
GSK-3α, IC50: 10 nM
GSK-3β, IC50: 6.7 nM
98.01%
CHIR-98014  
GSK-3α, IC50: 0.65 nM
GSK-3β, IC50: 0.58 nM
≥98.0%
AZD1080  
GSK-3α, pKi: 8.2
GSK-3β, pKi: 7.5
≥98.0%
R547  
GSK-3α, IC50: 46 nM
GSK-3β, IC50: 260 nM
99.66%
9-ING-41    
GSK-3β, IC50: 0.71 μM
99.32%
BRD0705  
GSK3α, IC50: 66 nM
GSK3α, Kd: 4.8 μM
GSK-3β(WT), IC50: 515 nM
98.41%
SB 415286  
hGSK-3α, IC50: 77.5 nM
hGSK-3β, IC50: 77.5 nM
99.72%
IM-12    
GSK-3β, IC50: 53 nM
98.30%
AZD2858  
GSK-3α, IC50: 0.9 nM
GSK-3β, IC50: 5 nM
99.42%
1-Azakenpaullone    
GSK-3β, IC50: 18 nM
≥98.0%
Indirubin-3'-monoxime    
GSK-3β, IC50: 22 nM
99.89%
BIO-acetoxime  
GSK-3α, IC50: 10 nM
GSK-3β, IC50: 10 nM
≥98.0%
CP21R7    
GSK-3β, IC50: 1.8 nM
99.77%
Bikinin
GSK-3
    99.94%
GNF4877    
GSK3β, IC50: 16 nM
98.85%
GSK-3β inhibitor 1    
GSK-3β, IC50: 4.9 nM
98.07%
SAR502250    
hGSK-3β, IC50: 12 nM
99.90%
KY19382    
GSK3β, IC50: 10 nM
98.04%
K00546
GSK-3, IC50: 140 nM
    98.78%
A 1070722  
GSK-3α, Ki: 0.6 nM
GSK-3β, Ki: 0.6 nM
≥99.0%
(R)-BRD3731  
GSK3α, IC50: 6.7 μM
GSK3β, IC50: 1.05 μM
98.22%
BRD3731  
GSK-3α, IC50: 215 nM
GSK-3β, IC50: 15 nM
98.02%
GSK-3β inhibitor 2    
GSK-3β, IC50: 1.1 nM
98.82%
TCS 21311    
GSK-3β, IC50: 3 nM
≥98.0%
BIP-135  
GSK-3α, IC50: 16 nM
GSK-3β, IC50: 21 nM
98.31%
EHT 5372  
GSK-3α, IC50: 7.44 nM
GSK-3β, IC50: 221 nM
Alsterpaullone  
GSK-3α, IC50: 4
GSK-3β, IC50: 4 nM
≥98.0%
5-Iodo-indirubin-3'-monoxime    
GSK-3β, IC50: 9 nM
99.50%
GSK-3 inhibitor 1
GSK-3
    99.89%
Cu(II)GTSM    
GSK3β
GSK-3β inhibitor 3    
GSK-3β, IC50: 6.6 μM
98.20%
Aloisine A  
GSK-3α, IC50: 1.5 μM
GSK-3β, IC50: 0.5 μM
Indirubin-3′-oxime    
GSK-3β
2B-(SP)  
GSK-3α
GSK-3β
2B-(SP) (TFA)  
GSK-3α
GSK-3β
Phospho-Glycogen Synthase Peptide-2(substrate)
GSK-3
   
Phospho-Glycogen Synthase Peptide-2(substrate) TFA
GSK-3
   
Indirubin-3'-monoxime-5-sulphonic acid    
GSK-3β, IC50: 80 nM