1. Signaling Pathways
  2. NF-κB
  3. IKK
  4. IKK Inhibitors

IKK Inhibitors

IKK-α

IKK-β

IKK

IKKε

TBK1

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

IKK Inhibitors
Product Name IKK-α IKK-β IKK IKKε TBK1 Purity
Resveratrol  
IKKβ, IC50: 1 μM
      99.70%
BX795      
IKKε, IC50: 41 nM
TBK1, IC50: 6 nM
99.33%
GSK8612        
TBK1, pIC50: 6.8
98.79%
Amlexanox      
IKKε, IC50: 1-2 μM
TBK1, IC50: 1-2 μM
99.32%
BAY-985      
IKKε, IC50: 2 nM
TBK1, IC50: 2 nM (low ATP)
TBK1, IC50: 30 nM (high ATP)
(Rac)-BAY-985        
TBK1, IC50: 1.5 nM
TBK1/IKKε-IN-4      
IKKε, IC50: 59 nM
TBK1, IC50: 13 nM
MLN120B  
IKKβ, IC50: 60 nM
      99.56%
BMS-345541 hydrochloride
IKK-1, IC50: 4 μM
IKK-2, IC50: 0.3 μM
      99.77%
MRT67307      
IKKε, IC50: 160 nM (at 0.1 mM ATP)
TBK1, IC50: 19 nM (at 0.1 mM ATP)
99.34%
TPCA-1  
IKK-2, IC50: 17.9 nM
      99.58%
IMD-0354  
IKKβ
      99.46%
ACHP Hydrochloride
IKK-α, IC50: 250 nM
IKK-β, IC50: 8.5 nM
      98.03%
SC-514  
IKK-2, IC50: 11.2 μM
      99.99%
BMS-345541
IKK-1, IC50: 4 μM
IKK-2, IC50: 0.3 μM
      99.17%
PS-1145    
IKK, IC50: 88 nM
    99.88%
LY2409881  
IKK2, IC50: 30 nM
     
BI605906  
IKKβ, IC50: 380 nM (at 0.1 mM ATP)
      99.64%
Bay 65-1942 hydrochloride  
IKKβ
      99.05%
TBK1/IKKε-IN-2      
IKKε, IC50: 3.9 nM (at 10 μM ATP)
TBK1, IC50: 0.6 nM (at 5 μM ATP)
98.50%
AZD3264  
IKK2
      98.77%
Vinpocetine    
IKK, IC50: 17.17 μM
    99.77%
LY2409881 trihydrochloride  
IKK2, IC50: 30 nM
      98.89%
GSK319347A  
IKK2, IC50: 790 nM
 
IKK-ε, IC50: 469 nM
TBK1, IC50: 93 nM
98.93%
IMD-0560  
IKKβ
      98.68%
IKK-IN-1    
IKK
    95.04%
Bay 65-1942 free base  
IKKβ
     
IKK 16 hydrochloride
IKK1, IC50: 200 nM
IKK2, IC50: 40 nM
IKK, IC50: 70 nM
   
BMS-066  
IKKβ, IC50: 9 nM
     
HPN-01
IKK-α, pIC50: 6.4
IKK-β, pIC50: 7.0
 
IKK-ε, pIC50: <4.8
 
INH14
IKKα, IC50: 8.97 μM
IKKβ, IC50: 3.59 μM
      >98.0%
Ertiprotafib  
IKK-β, IC50: 400 nM
     
TBK1/IKKε-IN-1      
IKKε, IC50: 100 nM
TBK1, IC50: 100 nM