1. Signaling Pathways
  2. Cytoskeleton
  3. Integrin
  4. Integrin Inhibitors

Integrin Inhibitors

αvβ1

αvβ3

αvβ5

αvβ6

αvβ8

α5β1

α1β1

α2β1

α4β1

α6β1

α9β1

αIIbβ3

α4β7

αLβ2

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Integrin Inhibitors, Agonists & Antagonists
Product Name αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α6β1 α9β1 αIIbβ3 α4β7 αLβ2 Purity
BIO5192 hydrate              
α2β1, IC50: 1053 nM
α4β1, IC50: 1.8 nM
 
α9β1, IC50: 138 nM
 
α4β7, IC50: >500 nM
  >98.0%
MK-0429
αvβ1, IC50: 1.6 nM (inhibition of fibronectin-binding )
αvβ3, IC50: 2.8 nM (inhibition of vitronectin-binding)
αvβ5, IC50: 0.1 nM (inhibition of vitronectin-binding)
αvβ6, IC50: 0.7 nM (inhibition of LAP-binding)
αvβ8, IC50: 0.5 nM (inhibition of LAP-binding)
α5β1, IC50: 12.2 nM (inhibition of fibronectin-binding)
                99.73%
Integrin modulator 1                
α4β1, IC50: 9.8 nM
         
BIO-1211          
α5β1, IC50: >100 μM
α1β1, IC50: >100 μM
 
α4β1, IC50: 4 nM
α6β1, IC50: >100 μM
 
αIIbβ3, IC50: >100 μM
α4β7, IC50: 2 μM
αLβ2, IC50: >100 μM
Echistatin  
αvβ3
     
α5β1
         
αIIbβ3
   
Echistatin TFA  
αvβ3
     
α5β1
         
αIIbβ3
   
BOP sodium                
α4β1
 
α9β1
     
THI0019                
α4β1, EC50: 1-2 μM
         
HSDVHK-NH2  
αvβ3, IC50: 2.74 nM