1. Epigenetics
    JAK/STAT Signaling
    Stem Cell/Wnt
  2. JAK
  3. JAK Inhibitors

JAK Inhibitors

JAK1

JAK2

JAK3

Tyk2

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

JAK Inhibitors
Product Name JAK1 JAK2 JAK3 Tyk2 Purity
Tyk2-IN-4      
Tyk2
99.76%
BMS-066      
Tyk2, IC50: 72 nM
Momelotinib
JAK1, IC50: 11 nM
JAK2, IC50: 18 nM
JAK3, IC50: 155 nM
  98.11%
AZD-1480
JAK1, IC50: 1.3 nM
JAK2, IC50: 0.4 nM
    99.37%
Fedratinib  
JAK2, IC50: 3 nM
JAK2(V617F), IC50: 3 nM
    98.62%
CHZ868  
JAK2, IC50: 110 nM
    98.33%
AT9283  
JAK2, IC50: 1.2 nM
JAK3, IC50: 1.1 nM
  99.13%
Filgotinib
JAK1, IC50: 10 nM
JAK2, IC50: 28 nM
JAK3, IC50: 810 nM
Tyk2, IC50: 116 nM
99.64%
Itacitinib
JAK1
      99.87%
Gandotinib  
JAK2, IC50: 3 nM
JAK3, IC50: 48 nM
Tyk2, IC50: 44 nM
99.96%
Peficitinib
JAK1, IC50: 3.9 nM
JAK2, IC50: 5 nM
JAK3, IC50: 0.7 nM
Tyk2, IC50: 4.8 nM
99.43%
Cucurbitacin I  
JAK2
    >98.0%
Decernotinib
JAK1, Ki: 11 nM
JAK2, Ki: 13 nM
JAK3, Ki: 2.5 nM
Tyk2, Ki: 11 nM
98.91%
Baricitinib phosphate
JAK1, IC50: 5.9 nM
JAK2, IC50: 5.7 nM
JAK3, IC50: 560 nM
Tyk2, IC50: 53 nM
99.49%
CEP-33779  
JAK2, IC50: 1.8 nM
JAK3, IC50: 150 nM
  98.04%
Delgocitinib
JAK1, IC50: 2.8 nM
JAK2, IC50: 2.6 nM
JAK3, IC50: 13 nM
Tyk2, IC50: 58 nM
99.14%
BMS-911543
JAK1, IC50: 75 nM
JAK2, IC50: 1.1 nM
JAK3, IC50: 360 nM
Tyk2, IC50: 66 nM
98.03%
Ilginatinib
JAK1, IC50: 33 nM
JAK2, IC50: 0.72 nM
JAK3, IC50: 39 nM
Tyk2, IC50: 22 nM
98.27%
TYK2-IN-2      
Tyk2
99.41%
SAR-20347
JAK1, IC50: 23 nM
JAK2, IC50: 26 nM
JAK3, IC50: 41 nM
Tyk2, IC50: 0.6 nM
97.00%
AZ960  
JAK2, Ki: 0.45 nM
JAK2, IC50: <3 nM
JAK3, IC50: 9 nM
  98.04%
WHI-P154    
JAK3, IC50: 1.8 μM
  98.14%
PF-06651600    
JAK3, IC50: 33.1 nM
  99.98%
Oclacitinib maleate
JAK1, IC50: 10 nM
JAK2, IC50: 18 nM
JAK3, IC50: 99 nM
Tyk2, IC50: 84 nM
99.53%
ZM39923 hydrochloride
JAK1, pIC50: 4.4
 
JAK3, pIC50: 7.1
  >98.0%
JANEX-1    
JAK3, IC50: 78 μM
  99.84%
NVP-BSK805 dihydrochloride
JAK1 JH1, IC50: 31.63 nM
JAK2 JH1, IC50: 0.48 nM
FL JAK2 V617F, IC50: 0.56 nM
FL JAK2 wt, IC50: 0.58 nM
JAK3 JH1, IC50: 18.68 nM
TYK2 JH1, IC50: 10.76 nM
98.00%
Itacitinib adipate
JAK1
      98.78%
WHI-P97    
JAK3, IC50: 11 μM
  99.48%
XL019  
JAK2, IC50: 2.2 nM
JAK3, IC50: 214.2 nM
  >98.0%
GLPG0634 analog    
JAK3, IC50: <100 nM
Tyk2, IC50: <100 nM
98.00%
Ilginatinib hydrochloride
JAK1, IC50: 33 nM
JAK2, IC50: 0.72 nM
JAK3, IC50: 39 nM
Tyk2, IC50: 22 nM
JAK3-IN-1
JAK1, IC50: 896 nM
JAK2, IC50: 1050 nM
JAK3, IC50: 4.8 nM
  99.16%
Momelotinib sulfate
JAK1, IC50: 11 nM
JAK2, IC50: 18 nM
JAK3, IC50: 155 nM
  >96.0%
AZD-4205
JAK1, IC50: 73 nM
     
NSC 42834  
JAK2-WT, IC50: 15 μM
JAK2-V617F, IC50: 28 μM
    95.5%
NVP-BSK805
JAK1 JH1, IC50: 31.63 nM
JAK2 JH1, IC50: 0.48 nM
FL JAK2 V617F, IC50: 0.56 nM
FL JAK2 wt, IC50: 0.58 nM
JAK3 JH1, IC50: 18.68 nM
TYK2 JH1, IC50: 10.76 nM
JAK3-IN-6    
JAK3, IC50: 0.15 nM
 
Momelotinib Mesylate
JAK1, IC50: 11 nM
JAK2, IC50: 18 nM
JAK3, IC50: 155 nM
 
Ruxolitinib sulfate
JAK1, IC50: 3.3 nM
JAK2, IC50: 2.8 nM
JAK3, IC50: 428 nM
Tyk2, IC50: 19 nM
ZM39923
JAK1, pIC50: 4.4
 
JAK3, pIC50: 7.1
 
JAK3-IN-7    
JAK3, IC50: 0.01 μM