1. Signaling Pathways
  2. MAPK/ERK Pathway
  3. MAP4K
  4. MAP4K Inhibitors

MAP4K Inhibitors

MAP4K2/GCK

MAP4K3/GLK

MAP4K4/HGK

MAP4K5/KHS1

MAP4K6/MINK1

MAP4K7/TNIK

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

MAP4K Inhibitors
Product Name MAP4K2/GCK MAP4K3/GLK MAP4K4/HGK MAP4K5/KHS1 MAP4K6/MINK1 MAP4K7/TNIK Purity
NG25
MAP4K2, IC50: 21.7 nM
          99.45%
NCB-0846          
TNIK, IC50: 21 nM
99.55%
PF-06260933    
MAP4K4, IC50: 3.7 nM
      99.69%
GNE 220 Hydrochloride    
MAP4K4, IC50: 7 nM
MAP4K5, IC50: 9 nM
MAP4K6, IC50: 1.1 μM
  98.32%
DMX-5804
GCK/MAP4K2, pIC50: 6.50
GLK/MAP4K3, pIC50: 4.95
MAP4K4, IC50: 3 nM
MAP4K4, pIC50: 8.55
KHS/MAP4K5, pIC50: 6.36
MINK1/MAP4K6, pIC50: 8.18
TNIK/MAP4K7, pIC50: 7.96
99.90%
TAK1/MAP4K2 inhibitor 1
MAP4K2, IC50: 18.2 nM
          99.70%
GNE 220    
MAP4K4, IC50: 7 nM
MAP4K5, IC50: 9 nM
MAP4K6, IC50: 1.1 μM