1. Signaling Pathways
  2. MAPK/ERK Pathway
  3. MEK
  4. MEK Inhibitors

MEK Inhibitors

MEK1

MEK2

MEK5

MEK

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

MEK Inhibitors, Antagonists & Activators
Product Name MEK1 MEK2 MEK5 MEK Purity
Trametinib
MEK1, IC50: 2 nM
MEK2, IC50: 2 nM
    99.44%
U0126-EtOH
MEK1, IC50: 70 nM
MEK2, IC50: 60 nM
    98.70%
PD98059
MEK1, IC50: 2-7 μM
MEK2, IC50: 50 μM
    99.94%
PD0325901
MEK1, Ki: 1 nM
MEK2, Ki: 1 nM
 
MEK, IC50: 0.33 nM
99.95%
Selumetinib
MEK1, IC50: 14 nM
   
MEK, IC50: 12 nM
99.87%
PD0325901-O-C2-dioxolane
MEK1
MEK2
   
Trametinib (DMSO solvate)
MEK1, IC50: 2 nM
MEK2, IC50: 2 nM
    99.77%
Cobimetinib
MEK1, IC50: 4.2 nM
      99.70%
Binimetinib      
MEK, IC50: 12 nM
99.55%
BIX02189    
MEK5, IC50: 1.5 nM
  99.99%
CI-1040
MEK1, IC50: 17 nM
      99.79%
Isorhamnetin
MEK1
      99.95%
Ro 5126766      
MEK, IC50: 160 nM
97.92%
TAK-733      
MEK, IC50: 3.2 nM
99.81%
Lidocaine      
MEK
99.89%
Refametinib
MEK1, IC50: 19 nM
MEK2, IC50: 47 nM
    99.82%
Lidocaine hydrochloride      
MEK
99.46%
Pimasertib
MEK1
MEK2
    99.70%
trans-Zeatin      
MEK
99.54%
GDC-0623
MEK1, Ki: 0.13 nM (+ATP)
      99.15%
Cobimetinib hemifumarate
MEK1, IC50: 4.2 nM
      >99.0%
SL327
MEK1, IC50: 180 nM
MEK2, IC50: 220 nM
    >98.0%
RO4987655
MEK1, IC50: 5.2 nM
MEK2, IC50: 5.2 nM
    99.17%
APS-2-79
MEK1
      99.31%
AZD8330
MEK1, IC50: 7 nM
MEK2, IC50: 7 nM
    99.14%
BI-847325  
MEK2, IC50: 4 nM
    99.14%
BIX02188    
MEK5, IC50: 4.3 nM
  99.49%
MEK inhibitor      
MEK
98.68%
PD318088      
MEK
99.88%
C16-PAF      
MEK
>98.0%
GW284543    
MEK5
  99.86%
U0126
MEK1, IC50: 70 nM
MEK2, IC50: 60 nM
   
Hypothemycin
MEK1, Ki: 17 nM
MEK2, Ki: 38 nM