1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. MMP
  4. MMP Inhibitors

MMP Inhibitors

MMP-1

MMP-2

MMP-3

MMP-8

MMP-9

MMP-13

MMP-14

ADAM10

ADAM17

MMP-7

MMP-12

MMP-10

MMP

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

MMP Inhibitors, Agonists & Activators
Product Name MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP Purity
Ilomastat
Fibroblast collagenase, Ki: 0.4 nM (Human skin)
MMP-1, IC50: 1.5 nM
MMP-2, IC50: 1.1 nM
MMP-3, IC50: 1.9 nM
 
MMP-9, IC50: 0.5 nM
                98.48%
Astragaloside IV  
MMP-2
   
MMP-9
                ≥98.0%
Otaplimastat                        
MMP
MMP13-IN-2  
MMP-2, IC50: 180 nM
MMP-3, IC50: 1100 nM
   
MMP-13, IC50: 0.036 nM
             
CP-544439
MMP-1, IC50: 420 nM
MMP-2, IC50: 1.6 nM
MMP-3, IC50: 16 nM
MMP-8, IC50: 1.4 nM
MMP-9, IC50: 12 nM
MMP-13, IC50: 0.75 nM
MMP-14, IC50: 7.4 nM
     
MMP-12, IC50: 0.24 nM
   
Cordycepin
MMP-1
 
MMP-3
                    ≥99.0%
Marimastat
MMP-1, IC50: 5 nM
MMP-2, IC50: 6 nM
MMP-3, IC50: 3 nM
     
MMP-14, IC50: 9 nM
   
MMP-7, IC50: 13 nM
      ≥98.0%
SB-3CT  
MMP-2, Ki: 13.9 nM
   
MMP-9, Ki: 600 nM
                99.35%
Salvianolic acid A        
MMP-9
                99.75%
TAPI-2                        
MMP, IC50: 20 μM
≥95.0%
Luteolin 7-O-glucuronide
MMP-1, IC50: 17.63 μM
 
MMP-3, IC50: 7.99 μM
MMP-8, IC50: 11.42 μM
MMP-9, IC50: 12.85 μM
MMP13, IC50: 0.03 μM
              ≥98.0%
Isofraxidin                  
MMP-7
      98.14%
MMP-9-IN-1        
MMP-9
                99.74%
Prinomastat hydrochloride
MMP-1, IC50: 79 nM
MMP-2, Ki: 0.05 nM
   
MMP-9, IC50: 5 nM
MMP-9, Ki: 0.26 nM
MMP-13, IC50: 6.3 nM
MMP-13, Ki: 0.3 nM
              ≥98.0%
Apigenin-7-glucuronide    
MMP-3, IC50: 12.87 μM
MMP-8, IC50: 22.39 μM
MMP-9, IC50: 17.52 μM
MMP13, IC50: 0.27 μM
              98.83%
UK 356618
MMP-1, IC50: 51 μM
MMP-2, IC50: 1.79 μM
MMP-3, IC50: 5.9 nM
 
MMP-9, IC50: 0.84 μM
MMP-13, IC50: 73 nM
MMP-14, IC50: 1.9 μM
            ≥98.0%
Ginkgolide C        
MMP-9
                ≥98.0%
Morroniside  
MMP2
   
MMP9
                ≥98.0%
ARP-100
MMP-1, IC50: >50 μM
MMP-2, IC50: 12 nM
MMP-3, IC50: 4.5 μM
 
MMP-9, IC50: 0.2 μM
       
MMP-7, IC50: >50 μM
      ≥99.0%
Auraptene  
MMP-2
                      99.52%
FSL-1 TFA        
MMP-9
                99.58%
UK-370106  
MMP-2, IC50: 34.2 μM
MMP-3, IC50: 23 nM
MMP-8, IC50: 1.75 μM
MMP-9, IC50: 30.4 μM
MMP-13, IC50: 2.3 μM
MMP-14, IC50: 66.9 μM
   
MMP-7, IC50: 5.8 μM
MMP-12, IC50: 42 nM
    ≥99.0%
PF-00356231 hydrochloride    
MMP-3, IC50: 0.39 μM
MMP-8, IC50: 1.7 μM
MMP-9, IC50: 0.98 μM
MMP13, IC50: 0.65 nM
       
MMP-12, IC50: 1.4 μM
    ≥99.0%
XL-784
MMP-1, IC50: 1900 nM
MMP-2, IC50: 0.81 nM
MMP-3, IC50: 120 nM
MMP-8, IC50: 10.8 nM
MMP-9, IC50: 18 nM
MMP13, IC50: 0.56 nM
              98.20%
S 3304        
MMP-9
                99.11%
Isoliquiritin apioside        
MMP9
                99.87%
CMC2.24
MMP-1, IC50: 69.8 μM
MMP-2, IC50: 4.8 μM
MMP-3, IC50: 2.9 μM
MMP-8, IC50: 4.5 μM
MMP-9, IC50: 8 μM
MMP-13, IC50: 2.7 μM
MMP-14, IC50: 15.3 μM
   
MMP-7, IC50: 5 μM
MMP-12, IC50: 2 μM
    96.48%
β-Anhydroicaritin    
MMP-3
                    98.43%
Prinomastat
MMP-1, IC50: 79 nM
MMP-2, Ki: 0.05 nM
MMP-3, IC50: 6..3 nM
MMP-3, Ki: 0.3 nM
 
MMP-9, IC50: 5 nM
MMP-9, Ki: 0.26 nM
                ≥95.0%
PD-166793
MMP-1, IC50: 6.0 μM
MMP-2, IC50: 4 nM
MMP-3, IC50: 7 nM
 
MMP-9, IC50: 7.9 μM
MMP-13, IC50: 8 nM
     
MMP-7, IC50: 7.2 μM
      ≥99.0%
MMPI-1154
MMP-1, IC50: 10 μM
MMP-2, IC50: 6.6 μM
   
MMP-9, IC50: 13 μM
MMP-13, IC50: 1.8 μM
              99.87%
DB04760          
MMP-13, IC50: 8 nM
              98.45%
Tanomastat  
MMP-2, Ki: 11 nM
MMP-3, Ki: 143 nM
 
MMP-9, Ki: 301 nM
MMP-13, Ki: 1470 nM
              ≥99.0%
Aderbasib              
ADAM10
ADAM17
       
Cipemastat
collagenases 1, Ki: 3.0 nM
gelatinase A, Ki: 154 nM
stromelysins 1, Ki: 527 nM
collagenases 2, Ki: 4.4 nM
gelatinase B, Ki: 59.1 nM
collagenases 3, Ki: 3.4 nM
             
MMP13-IN-3  
MMP-2, IC50: 18 μM
   
MMP-9, IC50: 8.9 μM
MMP-13, IC50: 1 nM
MMP-14, IC50: 8.3 μM
       
MMP-10, IC50: 16 μM
 
FFAGLDD        
MMP9
               
(R)-ND-336  
MMP-2, Ki: 127 nM
   
MMP-9, Ki: 19 nM
 
MMP-14, Ki: 119 nM
           
CP-471474
MMP-1, IC50: 1170 nM
MMP-2, IC50: 0.7 nM
MMP-3, IC50: 16 nM
 
MMP-9, IC50: 13 nM
MMP-13, IC50: 0.9 nM
             
MMP3 inhibitor 1
MMP-1, IC50: 14000 nM
MMP-2, IC50: 529 nM
MMP-3, IC50: 1 nM
 
MMP-9, IC50: 2420 nM
 
MMP-14, IC50: 20100 nM
           
CTTHWGFTLC, CYCLIC TFA  
MMP-2
   
MMP-9
               
BR351  
MMP-2, IC50: 4 nM
 
MMP-8, IC50: 2 nM
MMP-9, IC50: 11 nM
MMP13, IC50: 50 nM
             
SM-7368        
MMP-9
               
FFAGLDD TFA        
MMP9
               
XL-784 free base
MMP-1, IC50: 1900 nM
MMP-2, IC50: 0.81 nM
MMP-3, IC50: 120 nM
MMP-8, IC50: 10.8 nM
MMP-9, IC50: 18 nM
MMP-13, IC50: 0.56 nM
             
GW280264X              
ADAM10, IC50: 11.5 nM
ADAM17, IC50: 8 nM
       
ND-336  
MMP-2, Ki: 85 nM
   
MMP-9, Ki: 150 nM
 
MMP-14, Ki: 120 nM
           
CTTHWGFTLC, CYCLIC  
MMP-2
   
MMP-9