2. Signaling Pathways
  3. NF-κB
  4. NF-κB
  5. NF-κB Isoform

NF-κB

 

NF-κB Related Products (294):

Cat. No. Product Name Effect Purity
  • HY-18739
    Phorbol 12-myristate 13-acetate
    		Activator 99.66%
    Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a dual SphK and protein kinase C (PKC) activator.
  • HY-10227
    Bortezomib
    		Inhibitor 99.97%
    Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue.
  • HY-13453
    BAY 11-7082
    		Inhibitor 99.98%
    BAY 11-7082 is an IκBα phosphorylation and NF-κB inhibitor.
  • HY-100487
    TAK-243
    		Inhibitor 98.38%
    TAK-243 (MLN7243) is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor (IC50=1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global protein ubiquitination.
  • HY-13982
    JSH-23
    		Inhibitor 99.11%
    JSH-23 is an NF-κB inhibitor which inhibits NF-κB transcriptional activity with an IC50 of 7.1 μM in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7.
  • HY-18738
    Pyrrolidinedithiocarbamate ammonium
    		Inhibitor 99.04%
    Pyrrolidinedithiocarbamate ammonium (Ammonium pyrrolidinedithiocarbamate) is a selective and blood-brain barrier (BBB) permeable NF-κB inhibitor.
  • HY-N0822
    Shikonin
    		Inhibitor 99.80%
    Shikonin is a major component of a Chinese herbal medicine named zicao.
  • HY-N0197
    Baicalin
    		Inhibitor 99.17%
    Baicalin, as a flavonoid glycoside, is an allosteric carnitine palmityl transferase 1 (CPT1) activator.
  • HY-10257
    BAY 11-7085
    		Inhibitor 99.99%
    BAY 11-7085 (BAY 11-7083) is an inhibitor of NF-κB activation and phosphorylation of IκBα; it stabilizes IκBα with an IC50 of 10 μM.
  • HY-N0141
    Parthenolide
    		Inhibitor 98.09%
    Parthenolide is an NF-κB inhibitor, reduces histone deacetylase 1 (HDAC-1) and DNA methyltransferase 1 independent of NF-κB inhibition.
  • HY-10529
    Betulinic acid
    		Modulator ≥98.0%
    Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties.
  • HY-13812
    QNZ
    		Inhibitor 99.51%
    QNZ (EVP4593) shows strong inhibitory effects on NF-κB transcriptional activation and TNF-α production with IC50s of 11 and 7 nM, respectively.
  • HY-P0151
    SN50
    		Inhibitor 98.91%
    SN50 is a cell permeable inhibitor of NF-κB translocation.
  • HY-N2117
    Isoginkgetin
    		Inhibitor 99.73%
    Isoginkgetin is a pre-mRNA splicing inhibitor inhibitor.
  • HY-18935A
    CBL0137 hydrochloride
    		Inhibitor 99.66%
    CBL0137 hydrochloride is an inhibitor of the histone chaperone, FACT.
  • HY-N0452
    Hyperoside
    		Inhibitor 99.56%
    Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum.
  • HY-19357
    E3330
    		Inhibitor 99.34%
    E3330 (APX-3330) is a direct, orally active and selective inhibitor of Ape-1 (apurinic/apyrimidinic endonuclease 1)/Ref-1 (redox factor-1) redox.
  • HY-120501
    B022
    		Inhibitor 99.76%
    B022 is a potent and selective NF-κB-inducing kinase (NIK) inhibitor (Ki of 4.2 nM; IC50=15.1 nM).
  • HY-N0274
    Caffeic acid phenethyl ester
    		Inhibitor 99.96%
    Caffeic acid phenethyl ester is a NF-κB inhibitor.
  • HY-B0185
    Lidocaine
    		Inhibitor 99.96%
    Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence.