1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. PARP
  4. PARP Inhibitors

PARP Inhibitors

PARP

PARP1

PARP2

PARP3

PARP4

TNKS1/PARP5A

TNKS2/PARP5B

PARP10

PARP14

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

PARP Inhibitors & Activators
Product Name PARP PARP1 PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP10 PARP14 Purity
Olaparib  
PARP-1, IC50: 5 nM
PARP-2, IC50: 1 nM
   
tankyrase-1, IC50: 1.5 μM
      99.98%
Talazoparib  
PARP1, Ki: 1.2 nM
PARP2, Ki: 0.87 nM
            99.89%
Niraparib  
PARP-1, IC50: 3.8 nM
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
      99.97%
XAV-939  
ARTD1, IC50: 5500 nM
ARTD2, IC50: 479 nM
   
TNKS1, IC50: 5 nM
TNKS2, IC50: 2 nM
    98.71%
Veliparib  
PARP-1, Ki: 5.2 nM
PARP-2, Ki: 2.9 nM
            >98.0%
GeA-69                
PARP14, Kd: 2.1 μM
99.69%
Rucaparib phosphate  
PARP-1, Ki: 1.4 nM
              99.89%
Niraparib tosylate  
PARP-1, IC50: 3.8 nM
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
      99.52%
PJ34 hydrochloride
PARP, IC50: 110 nM
PARP-1, IC50: 110 nM
PARP-2, IC50: 86 nM
            97.68%
Pamiparib
PARP
                99.97%
Rucaparib Camsylate  
PARP-1, Ki: 1.4 nM
              99.92%
PJ34
PARP, IC50: 110 nM
PARP-1, IC50: 110 nM
PARP-2, IC50: 86 nM
            >98.0%
G007-LK          
TNKS1, IC50: 46 nM
TNKS2, IC50: 25 nM
    99.24%
NMS-P118  
PARP-1, Kd: 9 nM
PARP-2, Kd: 1390 nM
            99.80%
3-Aminobenzamide
PARP, IC50: 50 nM
                99.92%
AG14361  
PARP-1, Ki: 0.5 nM
              98.54%
Iniparib  
PARP1
              99.87%
A-966492  
PARP-1, Ki: 1 nM
PARP-2, Ki: 1.5 nM
            98.59%
AZD-2461  
PARP1, IC50: 5 nM
PARP2, IC50: 2 nM
PARP3, IC50: 200 nM
          98.39%
MN-64  
ARTD1, IC50: 19.1 μM
ARTD2, IC50: 39.4 μM
   
TNKS1, IC50: 6 nM
TNKS2, IC50: 72 nM
    98.22%
(8R,9S)-Talazoparib  
PARP-1, IC50: 144 nM
              95.08%
BGP-15
PARP, IC50: 120 μM
                >98.0%
WIKI4            
TNKS2, IC50: 26 nM
    99.77%
NVP-TNKS656    
PARP2, IC50: 32 μM
     
TNKS2, IC50: 6 nM
    99.31%
Niraparib R-enantiomer  
PARP-1, IC50: 2.4 nM
              99.37%
ME0328  
ARTD1/PARP1, IC50: 6.3 μM
ARTD2/PARP2, IC50: 10.8 μM
ARTD3/PARP3, IC50: 0.89 μM
 
ARTD5/TNKS1, IC50: 47.3 μM
ARTD6/TNKS2, IC50: 34.3 μM
ARTD10/PARP10, IC50: 71.3 μM
  99.34%
Niraparib hydrochloride  
PARP-1, IC50: 3.8 nM
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
      99.80%
RK-287107          
tankyrase-1, IC50: 14.3 nM
tankyrase-2, IC50: 10.6 nM
    99.81%
Dehydrocorydaline
PARP
               
K-756          
TNKS1, IC50: 31 nM
TNKS2, IC50: 36 nM
    >99.0%
Rucaparib  
PARP-1, Ki: 1.4 nM
             
UPF 1069  
PARP-1, IC50: 8 μM
PARP-2, IC50: 0.3 μM
            98.88%
PARP-2-IN-1    
PARP-2, IC50: 11.5 nM
           
NMS-P515  
PARP-1, Kd: 16 nM
PARP-1, IC50: 27 nM (in Hela cells)
             
PROTAC PARP1 degrader  
PARP1
             
5,​7,​4'-​Trimethoxyflavone
PARP
               
Verminoside  
PARP-1
             
INO-1001
PARP
               
Paris saponin VII  
PARP-1
             
5,7-Dihydroxychromone
PARP
               
PARP14 inhibitor H10                
PARP14, IC50: 490 nM
WD2000-012547  
PARP-1, pKi: 8.221