1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. PARP
  4. PARP Inhibitors

PARP Inhibitors

PARP

PARP1

PARP2

PARP3

PARP4

TNKS1/PARP5A

TNKS2/PARP5B

PARP10

PARP14

PARP7

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

PARP Inhibitors & Activators
Product Name PARP PARP1 PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP10 PARP14 PARP7 Purity
Olaparib  
PARP-1, IC50: 5 nM
PARP-2, IC50: 1 nM
   
tankyrase-1, IC50: 1.5 μM
        99.98%
Talazoparib  
PARP1, Ki: 1.2 nM
PARP2, Ki: 0.87 nM
              99.89%
Niraparib  
PARP-1, IC50: 3.8 nM
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
        99.97%
XAV-939  
ARTD1, IC50: 5500 nM
ARTD2, IC50: 479 nM
   
TNKS1, IC50: 5 nM
TNKS2, IC50: 2 nM
      98.71%
Veliparib  
PARP-1, Ki: 5.2 nM
PARP-2, Ki: 2.9 nM
              99.47%
RBN-2397                  
PARP-7, IC50: 3 nM
PARP-7, Kd: 1 nM
99.45%
RBN012759        
PARP4, IC50: 10 μM
   
PARP10, IC50: 1 μM
PARP14, IC50: <3 nM
PARP7, IC50: 4 μM
99.88%
Rucaparib phosphate  
PARP-1, Ki: 1.4 nM
                99.89%
Pamiparib
PARP
                  99.97%
Niraparib tosylate  
PARP-1, IC50: 3.8 nM
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
        99.81%
Rucaparib Camsylate  
PARP-1, Ki: 1.4 nM
                99.92%
PJ34
PARP, IC50: 110 nM
PARP-1, IC50: 110 nM
PARP-2, IC50: 86 nM
              >98.0%
G007-LK          
TNKS1, IC50: 46 nM
TNKS2, IC50: 25 nM
      99.24%
PJ34 hydrochloride
PARP, IC50: 110 nM
PARP-1, IC50: 110 nM
PARP-2, IC50: 86 nM
              98.01%
3-Aminobenzamide
PARP, IC50: 50 nM
                  99.92%
Rucaparib  
PARP-1, Ki: 1.4 nM
                99.27%
AG14361  
PARP-1, Ki: 0.5 nM
                98.54%
Iniparib  
PARP1
                99.87%
AZD-2461  
PARP1, IC50: 5 nM
PARP2, IC50: 2 nM
PARP3, IC50: 200 nM
            98.39%
NMS-P118  
PARP-1, Kd: 9 nM
PARP-2, Kd: 1390 nM
              99.80%
A-966492  
PARP-1, Ki: 1 nM
PARP-2, Ki: 1.5 nM
              99.47%
MN-64  
ARTD1, IC50: 19.1 μM
ARTD2, IC50: 39.4 μM
   
TNKS1, IC50: 6 nM
TNKS2, IC50: 72 nM
      98.22%
BGP-15
PARP, IC50: 120 μM
                  >98.0%
ME0328  
ARTD1/PARP1, IC50: 6.3 μM
ARTD2/PARP2, IC50: 10.8 μM
ARTD3/PARP3, IC50: 0.89 μM
 
ARTD5/TNKS1, IC50: 47.3 μM
ARTD6/TNKS2, IC50: 34.3 μM
ARTD10/PARP10, IC50: 71.3 μM
    99.34%
(8R,9S)-Talazoparib  
PARP-1, IC50: 144 nM
                95.08%
RK-287107          
tankyrase-1, IC50: 14.3 nM
tankyrase-2, IC50: 10.6 nM
      99.81%
Dehydrocorydaline
PARP
                  99.01%
WIKI4            
TNKS2, IC50: 26 nM
      99.77%
Niraparib (R-enantiomer)  
PARP-1, IC50: 2.4 nM
                99.50%
GeA-69                
PARP14, Kd: 2.1 μM
  99.69%
Niraparib hydrochloride  
PARP-1, IC50: 3.8 nM
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
        99.80%
K-756          
TNKS1, IC50: 31 nM
TNKS2, IC50: 36 nM
      >99.0%
NVP-TNKS656    
PARP2, IC50: 32 μM
     
TNKS2, IC50: 6 nM
      99.52%
UPF 1069  
PARP-1, IC50: 8 μM
PARP-2, IC50: 0.3 μM
              98.88%
5,​7,​4'-​Trimethoxyflavone
PARP
                  99.65%
BYK204165  
hPARP-1, pIC50: 7.35
mPARP-2, pIC50: 5.38
              99.68%
Paris saponin VII  
PARP-1
                >99.0%
PARP14 inhibitor H10                
PARP14, IC50: 490 nM
  98.16%
1,5-Isoquinolinediol
PARP, IC50: 0.18-0.37 μM
                  99.33%
Verminoside  
PARP-1
               
INO-1001
PARP
                  99.66%
5,7-Dihydroxychromone
PARP
                 
WD2000-012547  
PARP-1, pKi: 8.221