1. Signaling Pathways
  2. PROTAC
  3. PROTAC
  4. PROTAC Inhibitors

PROTAC Inhibitors

von Hippel-Lindau (VHL)

Cereblon

MDM2

cIAP1

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PROTAC Inhibitors
Product Name von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1 Purity
dBET1  
Cereblon
    99.24%
DT2216
VHL
     
PROTAC FKBP Degrader-3
VHL
     
VH032-PEG5-C6-Cl
VHL
      98.10%
BSJ-03-123  
Cereblon
    99.45%
PROTAC K-Ras Degrader-1  
Cereblon
    98.05%
MD-224    
MDM2, IC50: 1 nM
  99.74%
ZXH-3-26  
Cereblon
    98.39%
(S,R,S)-AHPC-PEG2-C4-Cl
VHL
      98.79%
SIAIS178
VHL
      99.48%
(S,R,S)-AHPC-PEG6-C4-Cl
VHL
      96.46%
(S,R,S)-AHPC-C6-PEG3-C4-Cl
VHL
      95.04%
BI-3663  
Cereblon
    98.14%
Homo-PROTAC cereblon degrader 1  
Cereblon
    99.00%
SD-36  
Cereblon
   
CP-10  
Cereblon
    98.03%
PROTAC BRD9 Degrader-1  
CRBN-DDB1, IC50: 48.9 nM
    99.37%
JH-XI-10-02  
Cereblon
    97.28%
FKBP12 PROTAC dTAG-13  
Cereblon
    >98.0%
PROTAC ERα Degrader-2      
cIAP1
98.02%
GNE-987
VHL
      98.90%
PROTAC MDM2 Degrader-3    
MDM2
  98.69%
Homo-PROTAC pVHL30 degrader 1
VHL
      99.56%
PROTAC MDM2 Degrader-1    
MDM2
 
PROTAC RAR Degrader-1      
cIAP1
95.01%
PROTAC CRBN Degrader-1
VHL
Cereblon
    99.34%
MS4078  
Cereblon
    98.07%
dFKBP-1  
Cereblon
    98.84%
FKBP12 PROTAC dTAG-7  
Cereblon
    >98.0%
PROTAC PARP1 degrader    
MDM2
 
PROTAC BRD4 Degrader-2  
Cereblon
   
PROTAC ERRα Degrader-2    
MDM2
 
MG-277    
MDM2
 
ARCC-4
VHL
     
PROTAC RIPK degrader-2
VHL
     
PROTAC BRD2/BRD4 degrader-1  
Cereblon
   
ARD-266
VHL
     
TD-165  
Cereblon, DC50: 20.4 nM
   
SJFδ
VHL
     
XZ739  
Cereblon
   
TL13-12  
Cereblon, IC50: 1.2 μM
   
PROTAC PD-1/PD-L1 degrader-1  
Cereblon
   
PROTAC MDM2 Degrader-4    
MDM2
 
PROTAC EED degrader-1
VHL
     
PROTAC ER Degrader-4
VHL
     
MS4077  
Cereblon
   
FKBP12 PROTAC RC32  
Cereblon
   
PROTAC ERRα Degrader-1    
MDM2
 
PROTAC Bcl-xL degrader-1      
cIAP1
(S)-GNE-987
VHL
     
CCT367766  
CRBN-DDB1, IC50: 490 nM
   
PROTAC MDM2 Degrader-2    
MDM2
 
PROTAC CDK2/9 Degrader-1  
Cereblon
   
TD-428  
Cereblon
   
SJFα
VHL
     
PROTAC IRAK4 degrader-1  
Cereblon
   
SJF620  
Cereblon
   
PROTAC AR Degrader-4      
cIAP1
TL13-112  
Cereblon, IC50: 2.4 μM
   
PROTAC EED degrader-2
VHL
     
INY-03-041  
Cereblon