1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Cytoskeleton
    Stem Cell/Wnt
    TGF-beta/Smad
  3. ROCK
  4. ROCK Inhibitors

ROCK Inhibitors

ROCK

ROCK1

ROCK2

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

ROCK Inhibitors & Activators
Product Name ROCK ROCK1 ROCK2 Purity
Y-27632 dihydrochloride  
ROCK-I, Ki: 220 nM
ROCK-II, Ki: 300 nM
99.83%
Y-27632  
ROCK-I, Ki: 220 nM
ROCK-II, Ki: 300 nM
99.91%
Chroman 1  
ROCK1, IC50: 52 pM
ROCK2, IC50: 1 pM
99.38%
Fasudil Hydrochloride  
p160ROCK, Ki: 0.33 μM
ROCK2, IC50: 0.158 μM
99.87%
Belumosudil  
ROCK1, IC50: 24 μM
ROCK2, IC50: 105 nM
99.77%
Sovesudil hydrochloride  
ROCK-I, IC50: 3.7 nM
ROCK-II, IC50: 2.3 nM
99.79%
HA-100 hydrochloride
ROCK
   
ROCK2-IN-5    
ROCK2, IC50: 2.13 μM
Thiazovivin
ROCK
    99.84%
Narciclasine
ROCK
    99.74%
Afuresertib
ROCK, IC50: 100 nM
    99.54%
H-1152 dihydrochloride    
ROCKII, IC50: 12 nM
99.88%
Ripasudil  
ROCK1, IC50: 51 nM
ROCK2, IC50: 19 nM
98.20%
AT13148  
ROCKI, IC50: 6 nM
ROCKII, IC50: 4 nM
99.42%
CMPD101    
ROCK2, IC50: 1.4 μM
98.74%
GSK269962A  
ROCK1, IC50: 1.6 nM
ROCK2, IC50: 4 nM
99.53%
Y-33075 dihydrochloride
ROCK, IC50: 3.6 nM
    98.75%
GSK180736A  
ROCK1, IC50: 100 nM
 
SR-3677  
ROCK-I, IC50: 56 nM
ROCK-II, IC50: 3 nM
99.90%
Y-33075
ROCK, IC50: 3.6 nM
    99.19%
RKI-1447  
ROCK1, IC50: 14.5 nM
ROCK2, IC50: 6.2 nM
98.06%
SAR407899  
ROCK-1, IC50: 276 nM
ROCK-2, IC50: 102 nM
99.86%
ROCK-IN-2  
ROCK-1, IC50: 0.6 nM
ROCK-2, IC50: 1.1 nM
98.03%
Hydroxyfasudil  
ROCK1, IC50: 0.73 μM
ROCK2, IC50: 0.72 μM
98.42%
ROCK inhibitor-2  
ROCK1, IC50: 17 nM
ROCK2, IC50: 2 nM
99.59%
Afuresertib hydrochloride
ROCK, IC50: 100 nM
    98.02%
GSK-25  
ROCK1, IC50: 7 nM
  99.68%
CRT0066854    
ROCK2, IC50: 620 nM
99.59%
SB-772077B dihydrochloride  
ROCK1, IC50: 5.6 nM
ROCK2, IC50: 6 nM
98.78%
BDP5290  
ROCK1, IC50: 5 nM
ROCK2, IC50: 50 nM
98.79%
Verosudil  
ROCK1, Ki: 2 nM
ROCK2, Ki: 2 nM
99.66%
SAR407899 hydrochloride  
ROCK-1, IC50: 276 nM
ROCK-2, IC50: 102 nM
98.66%
Hydroxyfasudil hydrochloride  
ROCK1, IC50: 0.73 μM
ROCK2, IC50: 0.72 μM
98.88%
Sovesudil  
ROCK-I, IC50: 3.7 nM
ROCK-II, IC50: 2.3 nM
98.31%
Rho-Kinase-IN-1  
ROCK1, Ki: 30.5 nM
ROCK2, Ki: 3.9 nM
99.91%
RKI-1447 dihydrochloride  
ROCK1, IC50: 14.5 nM
ROCK2, IC50: 6.2 nM
98.04%
HSD1590  
ROCK1, IC50: 1.22 nM
ROCK2, IC50: 0.51 nM
99.33%
CRT0066854 hydrochloride    
ROCKII, IC50: 620 nM
H-1152    
ROCKII, IC50: 12 nM
Fasudil  
p160ROCK, Ki: 0.33 μM
ROCK2, IC50: 0.158 μM
Hu7691 free base  
ROCK1, IC50: 354 nM
 
Hu7691  
ROCK1, IC50: 354 nM
 
Belumosudil mesylate  
ROCK1, IC50: 24 μM
ROCK2, IC50: 105 nM
ROCK2-IN-2    
ROCK2, IC50: 1 μM
Chroman 1 dihydrochloride  
ROCK1, IC50: 52 pM
ROCK2, IC50: 1 pM
GSK269962A hydrochloride  
ROCK1, IC50: 1.6 nM
ROCK2, IC50: 4 nM
Glycyl H-1152 hydrochloride    
ROCKII, IC50: 11.8 nM
PF-4950834  
ROCK1, IC50: 33.12 nM
ROCK2, IC50: 8.35 nM
RKI-1313  
ROCK1, IC50: 34 μM
ROCK2, IC50: 8 μM
Ripasudil free base  
ROCK1, IC50: 51 nM
ROCK2, IC50: 19 nM
ROCK-IN-1    
ROCK2, IC50: 1.2 nM