1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Stem Cell/Wnt
    TGF-beta/Smad
  3. ROCK
  4. ROCK Inhibitors

ROCK Inhibitors

ROCK

ROCK1

ROCK2

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

ROCK Inhibitors & Activators
Product Name ROCK ROCK1 ROCK2 Purity
Y-27632 dihydrochloride  
ROCK-I, Ki: 220 nM
ROCK-II, Ki: 300 nM
99.83%
Y-27632  
ROCK-I, Ki: 220 nM
ROCK-II, Ki: 300 nM
99.65%
Fasudil Hydrochloride  
p160ROCK, Ki: 0.33 μM
  99.91%
SLx-2119  
ROCK1, IC50: 24 μM
ROCK2, IC50: 105 nM
99.59%
ROCK inhibitor-2  
ROCK1, IC50: 17 nM
ROCK2, IC50: 2 nM
SB-772077B dihydrochloride  
ROCK1, IC50: 5.6 nM
ROCK2, IC50: 6 nM
>99.0%
Chroman 1    
ROCK2, IC50: 1 nM
99.76%
Y-33075 dihydrochloride
ROCK, IC50: 3.6 nM
    97.92%
Thiazovivin
ROCK
    99.32%
GSK269962A  
ROCK1, IC50: 1.6 nM
ROCK2, IC50: 4 nM
98.01%
RKI-1447  
ROCK1, IC50: 14.5 nM
ROCK2, IC50: 6.2 nM
97.26%
Azaindole 1  
ROCK-1, IC50: 0.6 nM
ROCK-2, IC50: 1.1 nM
99.46%
Ripasudil  
ROCK1, IC50: 51 nM
ROCK2, IC50: 19 nM
99.75%
GSK180736A  
ROCK1, IC50: 100 nM
  98.05%
SR-3677  
ROCK-I, IC50: 56 nM
ROCK-II, IC50: 3 nM
99.46%
H-1152 dihydrochloride    
ROCKII, IC50: 12 nM
>98.0%
AT13148  
ROCKI, IC50: 6 nM
ROCKII, IC50: 4 nM
99.54%
Hydroxyfasudil  
ROCK1, IC50: 0.73 μM
ROCK2, IC50: 0.72 μM
98.13%
BDP5290  
ROCK1, IC50: 5 nM
ROCK2, IC50: 50 nM
>98.0%
Y-33075
ROCK, IC50: 3.6 nM
    98.98%
SAR407899  
ROCK-1, IC50: 276 nM
ROCK-2, IC50: 102 nM
98.43%
Hydroxyfasudil hydrochloride  
ROCK1, IC50: 0.73 μM
ROCK2, IC50: 0.72 μM
99.40%
H-1152    
ROCKII, IC50: 12 nM
SAR407899 hydrochloride  
ROCK-1, IC50: 276 nM
ROCK-2, IC50: 102 nM
99.81%
Fasudil  
p160ROCK, Ki: 0.33 μM
 
ROCK2-IN-2    
ROCK2, IC50: 1 μM
Pentanoic acid
ROCK
   
Ripasudil free base  
ROCK1, IC50: 51 nM
ROCK2, IC50: 19 nM
ROCK-IN-1    
ROCK2, IC50: 1.2 nM