1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Stem Cell/Wnt
    TGF-beta/Smad
  3. ROCK
  4. ROCK Inhibitors

ROCK Inhibitors

ROCK

ROCK1

ROCK2

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

ROCK Inhibitors & Activators
Product Name ROCK ROCK1 ROCK2 Purity
Y-27632  
ROCK-I, Ki: 220 nM
ROCK-II, Ki: 300 nM
99.73%
Y-27632 dihydrochloride  
ROCK-I, Ki: 220 nM
ROCK-II, Ki: 300 nM
99.83%
Fasudil Hydrochloride  
p160ROCK, Ki: 0.33 μM
ROCK2, IC50: 0.158 μM
99.91%
Chroman 1    
ROCK2, IC50: 1 nM
99.90%
CMPD101    
ROCK2, IC50: 1.4 μM
GSK-25  
ROCK1, IC50: 7 nM
  99.68%
SLx-2119  
ROCK1, IC50: 24 μM
ROCK2, IC50: 105 nM
99.42%
Ripasudil  
ROCK1, IC50: 51 nM
ROCK2, IC50: 19 nM
99.75%
Thiazovivin
ROCK
    99.32%
Afuresertib
ROCK, IC50: 100 nM
    98.95%
GSK269962A  
ROCK1, IC50: 1.6 nM
ROCK2, IC50: 4 nM
98.12%
Y-33075 dihydrochloride
ROCK, IC50: 3.6 nM
    97.92%
ROCK-IN-2  
ROCK-1, IC50: 0.6 nM
ROCK-2, IC50: 1.1 nM
99.46%
RKI-1447  
ROCK1, IC50: 14.5 nM
ROCK2, IC50: 6.2 nM
97.26%
Y-33075
ROCK, IC50: 3.6 nM
    98.98%
AT13148  
ROCKI, IC50: 6 nM
ROCKII, IC50: 4 nM
99.54%
GSK180736A  
ROCK1, IC50: 100 nM
  97.03%
H-1152 dihydrochloride    
ROCKII, IC50: 12 nM
>98.0%
Hydroxyfasudil  
ROCK1, IC50: 0.73 μM
ROCK2, IC50: 0.72 μM
98.11%
SAR407899  
ROCK-1, IC50: 276 nM
ROCK-2, IC50: 102 nM
99.97%
SR-3677  
ROCK-I, IC50: 56 nM
ROCK-II, IC50: 3 nM
99.91%
Afuresertib hydrochloride
ROCK, IC50: 100 nM
    98.02%
BDP5290  
ROCK1, IC50: 5 nM
ROCK2, IC50: 50 nM
>98.0%
Rho-Kinase-IN-1  
ROCK1, Ki: 30.5 nM
ROCK2, Ki: 3.9 nM
99.72%
ROCK inhibitor-2  
ROCK1, IC50: 17 nM
ROCK2, IC50: 2 nM
99.59%
SAR407899 hydrochloride  
ROCK-1, IC50: 276 nM
ROCK-2, IC50: 102 nM
>98.0%
H-1152    
ROCKII, IC50: 12 nM
Hydroxyfasudil hydrochloride  
ROCK1, IC50: 0.73 μM
ROCK2, IC50: 0.72 μM
99.40%
Fasudil  
p160ROCK, Ki: 0.33 μM
ROCK2, IC50: 0.158 μM
ROCK2-IN-2    
ROCK2, IC50: 1 μM
Pentanoic acid
ROCK
   
SB-772077B dihydrochloride  
ROCK1, IC50: 5.6 nM
ROCK2, IC50: 6 nM
>99.0%
Ripasudil free base  
ROCK1, IC50: 51 nM
ROCK2, IC50: 19 nM
ROCK-IN-1    
ROCK2, IC50: 1.2 nM