1. Signaling Pathways
  2. TGF-beta/Smad
  3. TGF-β Receptor
  4. TGF-β Receptor Inhibitors

TGF-β Receptor Inhibitors

ALK2

ALK3

ALK6

ALK5

ALK4

ALK7

TGFBR1

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

TGF-β Receptor Inhibitors
Product Name ALK2 ALK3 ALK6 ALK5 ALK4 ALK7 TGFBR1 Purity
SB-431542      
ALK5, IC50: 94 nM
      99.89%
Dorsomorphin dihydrochloride
ALK2
ALK3
ALK6
        99.91%
Dorsomorphin
ALK2
ALK3
ALK6
        99.65%
AZ12601011            
TGFBR1, IC50: 18 nM
TGFBR1, Kd: 2.9 nM
LDN193189
ALK2, IC50: 5 nM
ALK3, IC50: 30 nM
          95.92%
LDN193189 Tetrahydrochloride
ALK2, IC50: 5 nM
ALK3, IC50: 30 nM
          99.92%
Vactosertib      
ALK5, IC50: 12.9 nM
      99.58%
Vactosertib Hydrochloride      
ALK5, IC50: 12.9 nM
      98.57%
ALK2-IN-2
ALK2, IC50: 9 nM
            99.90%