1. Signaling Pathways
  2. TGF-beta/Smad
  3. TGF-β Receptor
  4. TGF-β Receptor Inhibitors

TGF-β Receptor Inhibitors

ALK2

ALK3

ALK6

ALK5

ALK4

ALK7

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

TGF-β Receptor Inhibitors
Product Name ALK2 ALK3 ALK6 ALK5 ALK4 ALK7 Purity
SB-431542      
ALK5, IC50: 94 nM
    99.89%
Dorsomorphin
ALK2
ALK3
ALK6
      ≥98.0%
Dorsomorphin dihydrochloride
ALK2
ALK3
ALK6
      99.91%
A 83-01      
ALK5, IC50: 12 nM
ALK4, IC50: 45 nM
ALK7, IC50: 7.5 nM
≥98.0%
A 83-01 sodium salt      
ALK5, IC50: 12 nM
ALK4, IC50: 45 nM
ALK7, IC50: 7.5 nM
≥95.0%
LDN193189
ALK2, IC50: 5 nM
ALK3, IC50: 30 nM
        99.48%
LDN193189 Tetrahydrochloride
ALK2, IC50: 5 nM
ALK3, IC50: 30 nM
        98.04%
Vactosertib      
ALK5, IC50: 12.9 nM
    99.58%
Vactosertib Hydrochloride      
ALK5, IC50: 12.9 nM
    98.57%
ALK2-IN-2
ALK2, IC50: 9 nM
          99.90%
AZ12601011        
ALK4
ALK7
99.25%
ALK2-IN-4
ALK2
          99.86%
OD36
ALK2, Kd: 37 nM
ALK2, IC50: 47 nM
ALK2 R206H, IC50: 22 nM
         
TGFBR1-IN-1      
ALK5, IC50: 10-100 nM
   
IN-1130      
ALK5
   
EW-7195      
ALK5, IC50: 4.83 nM
   
ALK2-IN-4 succinate
ALK2
          99.73%