1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. mGluR
  4. mGluR Inhibitors

mGluR Inhibitors

mGluR8

mGluR6

mGluR7

mGluR5

mGluR4

mGluR2

mGluR3

mGluR1

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

mGluR Inhibitors, Agonists, Antagonists & Modulators
Product Name mGluR8 mGluR6 mGluR7 mGluR5 mGluR4 mGluR2 mGluR3 mGluR1 Purity
DHPG      
mGluR 5
     
mGluR 1
>97.0%
VU0650786            
mGluR3, IC50: 392 nM
  99.97%
LY2812223          
mGluR2, Ki: 144 nM
mGluR3, Ki: 156 nM
  >98.0%
VU0364770  
mGlu6, EC50: 6.8 μM
 
mGlu5, EC50: 17.9 μM
Rat mGlu4, EC50: 290 nM
Human mGlu4, EC50: 1.1 μM
      99.57%
Foliglurax monohydrochloride        
mGlu4, EC50: 79 nM
      98.93%
L-APB
mGlu8, EC50: 0.29 μM
mGlu6, EC50: 1.0 μM
mGlu7, EC50: 249 μM
 
mGlu4, EC50: 0.13 μM
      >99.0%
LY2794193          
mGluR2, EC50: 47.5
mGluR2, Ki: 412
mGluR3, EC50: 0.47 nM
mGluR3, Ki: 0.927 nM
  99.88%
Xanthurenic acid          
mGluR2
mGluR3
  98.17%
(R)-ADX-47273      
mGlu5, EC50: 168 nM
        99.25%
CHPG sodium salt      
mGlu5
       
VU6001376        
mGlu4, EC50: 50.1 nM
     
Foliglurax        
mGlu4, EC50: 79 nM
     
CHPG      
mGlu5
       
VU0652835      
mGlu5, IC50: 81 nM
       
LY3020371 hydrochloride          
mGluR2, Ki: 5.3 nM
mGluR3, Ki: 2.5 nM
 
Fenobam      
rat mGluR5, Kd: 54 nM
human mGluR5, Kd: 31 nM
        98.53%
VU0364770 hydrochloride  
mGlu6, EC50: 6.8 μM
 
mGlu5, EC50: 17.9 μM
Rat mGlu4, EC50: 290 nM
Human mGlu4, EC50: 1.1 μM
     
LY 541850          
mGluR2, IC50: 0.161 μM
mGluR3, IC50: 1.05 μM
 
FTIDC      
mGlu5, IC50: 6200 nM
     
mGluR1a, IC50: 5.8 nM