1. Signaling Pathways
  2. PI3K/Akt/mTOR
  3. mTOR
  4. mTOR Inhibitors

mTOR Inhibitors

mTOR

mTORC1

mTORC2

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

mTOR Inhibitors & Activators
Product Name mTOR mTORC1 mTORC2 Purity
Rapamycin  
mTOR, IC50: 0.1 nM (in HEK293 cells )
  99.93%
Everolimus  
mTOR, IC50: 5-6 nM
  98.79%
MHY1485  
mTORC1
mTORC2
99.05%
JR-AB2-011    
mTORC2, IC50: 0.36 μM
98.09%
Pomiferin
mTOR, IC50: 6.2 μM
    97.36%
BGT226
mTOR
   
Sapanisertib
mTOR, IC50: 1 nM
    99.06%
Dactolisib
mTOR, IC50: 20.7 nM
    99.13%
Vistusertib
mTOR, IC50: 2.81 nM
    98.80%
LY3023414
mTOR, IC50: 165 nM
    99.77%
Salidroside
mTOR
    98.50%
PI-103  
mTORC1, IC50: 20 nM
mTORC2, IC50: 83 nM
99.86%
Temsirolimus  
mTOR, IC50: 1.76 μM
  99.56%
Torkinib
mTOR, IC50: 8 nM
mTORC1, IC50: 30 nM
mTORC2, IC50: 58 nM
95.47%
PF-04691502
mTOR, Ki: 16 nM
    99.49%
3BDO
mTOR
    99.67%
Omipalisib  
mTORC1, Ki: 0.18 nM
mTORC2, Ki: 0.3 nM
99.31%
OSI-027
mTOR, IC50: 4 nM
mTORC1, IC50: 22 nM
mTORC2, IC50: 65 nM
99.40%
Bimiralisib
mTOR, IC50: 89 nM
    98.90%
Deforolimus  
mTOR
  98.46%
Gedatolisib
mTOR, IC50: 1.6 nM
    99.11%
Apitolisib
mTOR, Ki: 17 nM
    99.13%
PI-103 Hydrochloride  
mTORC1, IC50: 20 nM
mTORC2, IC50: 83 nM
99.78%
Voxtalisib
mTOR, IC50: 157 nM
mTORC1, IC50: 160 nM
mTORC2, IC50: 910 nM
98.93%
CC-115
mTOR, IC50: 21 nM
    96.64%
L-Leucine  
mTORC1
  >98.0%
PP121
mTOR, IC50: 10 nM
    98.89%
GDC-0084
mTOR, Ki: 70 nM
    99.28%
Dactolisib Tosylate
mTOR, IC50: 20.7 nM
    99.89%
PQR620  
mTORC1
mTORC2
98.06%
CC-223
mTOR, IC50: 16 nM
    99.43%
BGT226 maleate
mTOR
    99.76%
CZ415
mTOR, pIC50: 8.07
    98.43%
WAY-600
mTOR, IC50: 9 nM
    95.41%
PF-04979064
mTOR, Ki: 1.42 nM
    99.75%
PKI-402
mTOR, IC50: 3 nM
    99.44%
ETP-46464
mTOR, IC50: 0.6 nM
    99.13%
GNE-317
mTOR
    99.26%
WYE-132
mTOR, IC50: 0.19 nM
    98.61%
GSK1059615
mTOR, IC50: 12 nM
    98.91%
GNE-477
mTOR, Ki: 21 nM
    95.81%
GNE-493
mTOR, IC50: 30 nM
    95.12%
VS-5584
mTOR, IC50: 37 nM
    98.01%
Rutin hydrate
mTOR
    >98.0%
CC-115 hydrochloride
mTOR, IC50: 21 nM
    97.22%
mTOR inhibitor-3
mTOR, Ki: 1.5 nM
    98.54%
GDC-0349
mTOR, Ki: 3.8 nM
    98.20%
XL388
mTOR, IC50: 9.9 nM
    98.46%
NSC781406
mTOR, IC50: 5.4 nM
    99.55%
Palomid 529  
TORC1
TORC2
99.42%
DL001  
mTORC1, IC50: 74.9 pM
 
mTOR inhibitor-2
mTOR, IC50: 7 nM
   
PI3K/mTOR Inhibitor-2
mTOR, IC50: 4.7 nM
    99.45%
HDACs/mTOR Inhibitor 1
mTOR, IC50: 1.2 nM
    99.12%
PI3K/mTOR Inhibitor-1
mTOR, IC50: 186 nM
   
(+)-Usnic acid  
mTORC1
mTORC2
Arnicolide D
mTOR
   
FT-1518  
mTORC1
mTORC2
PQR-530  
mTORC1
mTORC2
PI3Kα/mTOR-IN-1
mTOR, Ki: 10.6 nM