1. Cell Cycle/DNA Damage
  2. Checkpoint Kinase (Chk)
  3. CHK-IN-1

CHK-IN-1 

Cat. No.: HY-U00345
Handling Instructions

CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.

For research use only. We do not sell to patients.

CHK-IN-1 Chemical Structure

CHK-IN-1 Chemical Structure

CAS No. : 1278405-51-8

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Description

CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.

IC50 & Target[1]

Chk1

 

Chk2

 

In Vitro

CHK-IN-1 can prevent DNA damage repair mechanism from arresting the cell cycle at the G2/M checkpoint[1].

Molecular Weight

407.89

Formula

C₁₈H₁₉ClFN₅OS

CAS No.

1278405-51-8

SMILES

O=C(C1=NN=C(N[[email protected]@H]2CNCCC2)C3=C1SC(C4=CC=CC(F)=C4)=C3)N.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

CHK-IN-1Checkpoint Kinase (Chk)Inhibitorinhibitorinhibit

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