1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GABA Receptor

(-)-Borneol (Synonyms: L-Borneol)

Cat. No.: HY-N1368B Purity: >98.0%
Handling Instructions

(-)-Borneol has a highly efficacious positive modulating action at GABA receptor with an EC50 of 237 μM.

For research use only. We do not sell to patients.

(-)-Borneol Chemical Structure

(-)-Borneol Chemical Structure

CAS No. : 464-45-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
100 mg USD 60 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Other Forms of (-)-Borneol:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

(-)-Borneol has a highly efficacious positive modulating action at GABA receptor with an EC50 of 237 μM.

IC50 & Target

EC50: 237 μM (GABA receptor)[1]

In Vitro

(-)-Borneol is an enantiomer of (+)-Borneol. (+)-Borneol is a natural bicyclic monoterpene used for analgesia and anesthesia in traditional Chinese medicine; enhances GABA receptor activity with an EC50 of 248 μM. At high concentrations (>1.5 mM), (-)-Borneol directly activates GABAA receptors producing 84% of the maximal GABA response indicative of a weak partial agonist action. (-)-Borneol produces dose-dependent positive modulation of the Cl- conductance generated by extremely low dose GABA at α1β2γ2L GABAA receptors[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.4830 mL 32.4149 mL 64.8298 mL
5 mM 1.2966 mL 6.4830 mL 12.9660 mL
10 mM 0.6483 mL 3.2415 mL 6.4830 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

154.25

Formula

C₁₀H₁₈O

CAS No.

464-45-9

SMILES

C[[email protected]@]1(C2(C)C)CC[[email protected]]2C[[email protected]]1O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
(-)-Borneol
Cat. No.:
HY-N1368B
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(-)-Borneol

Cat. No.: HY-N1368B