1. Cell Cycle/DNA Damage
    PI3K/Akt/mTOR
  2. DNA-PK

(R)-Nedisertib (Synonyms: (R)-M3814)

Cat. No.: HY-101570A
Handling Instructions

(R)-Nedisertib ((R)-M3814) is a less active R-enantiomer of Nedisertib, with an IC50 in the range of 7-30 nM for DNA-PK.

For research use only. We do not sell to patients.

(R)-Nedisertib Chemical Structure

(R)-Nedisertib Chemical Structure

CAS No. : 1637542-32-5

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 275 In-stock
Estimated Time of Arrival: December 31
5 mg USD 250 In-stock
Estimated Time of Arrival: December 31
10 mg USD 350 In-stock
Estimated Time of Arrival: December 31
25 mg USD 650 In-stock
Estimated Time of Arrival: December 31
50 mg USD 950 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Other Forms of (R)-Nedisertib:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

(R)-Nedisertib ((R)-M3814) is a less active R-enantiomer of Nedisertib, with an IC50 in the range of 7-30 nM for DNA-PK[1].

IC50 & Target[1]

DNA-PK

7-30 nM (IC50)

In Vitro

Rac-Nedisertib (Compound 135) less actively inhibits DNA-PK, with an IC50 in the range of 7-30 nM[1].

References
Molecular Weight

481.91

Formula

C₂₄H₂₁ClFN₅O₃

CAS No.

1637542-32-5

SMILES

ClC1=C([[email protected]@H](O)C2=NN=C(OC)C=C2)C=C(C3=C4C=CC(N5CCOCC5)=CC4=NC=N3)C(F)=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
(R)-Nedisertib
Cat. No.:
HY-101570A
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(R)-Nedisertib

Cat. No.: HY-101570A