2. Anti-infection Apoptosis
  3. Bacterial Parasite Apoptosis
  4. Aflatoxin M1

Aflatoxin M1 is a major metabolite of Aflatoxin B1. Aflatoxin M1 is an orally active mycotoxin produced by Aspergillus flavus and Aspergillus parasiticus. The level of toxicity associated with Aflatoxin is Aflatoxin B1>Aflatoxin M1>Aflatoxin G1>Aflatoxin B2>Aflatoxin M2>Aflatoxin G2.

For research use only. We do not sell to patients.

Aflatoxin M1 Chemical Structure

Aflatoxin M1 Chemical Structure

CAS No. : 6795-23-9

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Based on 1 publication(s) in Google Scholar

Other Forms of Aflatoxin M1:

Aflatoxin M1 Related Antibodies

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Description

Aflatoxin M1 is a major metabolite of Aflatoxin B1. Aflatoxin M1 is an orally active mycotoxin produced by Aspergillus flavus and Aspergillus parasiticus. The level of toxicity associated with Aflatoxin is Aflatoxin B1>Aflatoxin M1>Aflatoxin G1>Aflatoxin B2>Aflatoxin M2>Aflatoxin G2[1][2][3].

In Vitro

Aflatoxin M1 (0.5, 1 μg/mL, 24-72 h) inhibits the growth of Caco-2 cells in a time dose-dependent manner [2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Aflatoxin M1 Related Antibodies

Cell Viability Assay[2]

Cell Line: Caco-2
Concentration: 0.01, 0.05, 0.1, 0.5, 1 μg/mL
Incubation Time: 24, 48, 72 h
Result: Inhibited cell viability at concentrations 0.5 and 1 μg/mL.
In Vivo

Aflatoxin M1 (3.5g /kg, gavage once a day for 28 days) activates oxidative stress by altering the expression of PRODH and L-proline, and then induces apoptosis of downstream cells of CD-1 mice, thereby causing renal toxicity[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: CD-1 mice model[3]
Dosage: 3.5 g/kg
Administration: i.g. once a day for 28 days
Result: Elevated MDA level and decreased SOD, T-AOC.
Molecular Weight

328.27

Formula

C17H12O7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1CCC(C2=C(C3=C(O[C@]4([H])[C@@]3(O)C=CO4)C=C2OC)O5)=C1C5=O
Structure Classification
Initial Source

Aspergillus flavus and Aspergillus parasiticus
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.43%

COA (266 KB) RP-HPLC (465 KB)

Handling Instructions (2659 KB)
References
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Aflatoxin M1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aflatoxin M16795-23-9Aflatoxin M 1Aflatoxin M-1BacterialParasiteApoptosisMycotoxin Caco-2PRODHCD-1 miceSODInhibitorinhibitorinhibit

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