1. Cell Cycle/DNA Damage Anti-infection
  2. Antibiotic DNA/RNA Synthesis Bacterial
  3. Albomycin

Albomycin is an inhibitor of aminoacyl-tRNA synthetases with Trojan-horse effect. Albomycin is delivered by iron-chelator portion into bacterial through ferrichrome-specific transporter system. Albomycin combats against a wide range of Gram-positive and Gram-negative bacteria. Albomycin also serves as an efficient iron-scavenger of producer.

For research use only. We do not sell to patients.

Albomycin Chemical Structure

Albomycin Chemical Structure

CAS No. : 1414-39-7

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Description

Albomycin is an inhibitor of aminoacyl-tRNA synthetases with Trojan-horse effect. Albomycin is delivered by iron-chelator portion into bacterial through ferrichrome-specific transporter system. Albomycin combats against a wide range of Gram-positive and Gram-negative bacteria. Albomycin also serves as an efficient iron-scavenger of producer[1].

In Vitro

Albomycin also binds to FhuA, competing with ferrichrome, FhuA is a β-strand barrel buried in the outer membrane of E.coli. Otherwise, Albomycin binds to FhuD, a periplasmic subunit of the inner membrane ABC transporter FhuB/FhuC[1].
Albomycin remarkably inhibits the growth of Streptococcus pneumonia strains with minimal inhibitory concentrations (MIC) of 4-62 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CAS No.
SMILES

[ALBOMYCIN]

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Albomycin
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HY-142072
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