1. Metabolic Enzyme/Protease
    Anti-infection
  2. Aminoacyl-tRNA Synthetase
    Bacterial
  3. Antibacterial agent 92

Antibacterial agent 92 

Cat. No.: HY-146265
Handling Instructions

Antibacterial agent 92 (Compound 36k) is a triple-site aminoacyl-tRNA synthetase (aaRS) inhibitor with an IC50 of 0.58 μM against Salmonella enterica threonyl-tRNA synthetase (SeThrRS). Antibacterial agent 92 exhibits antibacterial activities.

For research use only. We do not sell to patients.

Antibacterial agent 92 Chemical Structure

Antibacterial agent 92 Chemical Structure

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Description

Antibacterial agent 92 (Compound 36k) is a triple-site aminoacyl-tRNA synthetase (aaRS) inhibitor with an IC50 of 0.58 μM against Salmonella enterica threonyl-tRNA synthetase (SeThrRS). Antibacterial agent 92 exhibits antibacterial activities[1].

IC50 & Target

IC50: 0.58 μM (SeThrRS)[1]

In Vitro

Antibacterial agent 92 (Compound 36k) binds to the ATP site of SeThrRS[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

650.48

Formula

C30H28Cl2F3N5O4

SMILES

O=C(NC[[email protected]@H](C1=CC(C2=CC=C(C=C2)C(F)(F)F)=CC=C1)NC([[email protected]@H](N)[[email protected]@H](C)O)=O)CCN3C=NC4=C(C3=O)C=C(Cl)C(Cl)=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
Antibacterial agent 92
Cat. No.:
HY-146265
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