2. Apoptosis
  3. Apoptosis
  4. Anticancer agent 39

Anticancer agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), induces the collapse of mitochondrial membrane potential (MMP)and thus induced apoptosis.Anticancer agent 39 inhibits cell cloning and migration.Anticancer agent 39 exhibits promising anti-proliferative activity against HGC-27 cells with IC50 value of 0.39 μM.

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Anticancer agent 39 Chemical Structure

Anticancer agent 39 Chemical Structure

CAS No. : 2762426-00-4

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Anticancer agent 39 Related Antibodies

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Description

Anticancer agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), induces the collapse of mitochondrial membrane potential (MMP)and thus induced apoptosis.Anticancer agent 39 inhibits cell cloning and migration.Anticancer agent 39 exhibits promising anti-proliferative activity against HGC-27 cells with IC50 value of 0.39 μM[1].

Molecular Weight

896.08

Formula

C50H65N5O10
CAS No.
SMILES

O[C@@]([C@]1([H])C2=C)([H])[C@@]3(C2=O)[C@]([C@H](C1)O)([H])C4(CCCC(C)5C)[C@]5([H])C[C@@]3([H])O[C@H]4OCCCC(N=N6)=CN6CCOCCOCCOCCN(C7=O)C(C8=CC=C(N9CCCCC9)C%10=C8C7=CC=C%10)=O
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Anticancer agent 39 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 392762426-00-4Anticancer agent39Anticancer agent-39ApoptosisJiyuan?Oridonin?Amitochondrial membrane potentialMMPcloningmigrationproliferative activityHGC-27Inhibitorinhibitorinhibit

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