1. Metabolic Enzyme/Protease
  2. Mitochondrial Metabolism
  3. Antimycin A1

Antimycin A1 

Cat. No.: HY-107406
Handling Instructions

Antimycin A1 is a specific electron transfer inhibitor of ubiquinol-cytochrome c oxidoreductase. Antimycin A1 inhibits angiogenesis through decrease in VEGF production caused by inhibition of HIF-1α activation.

For research use only. We do not sell to patients.

Antimycin A1 Chemical Structure

Antimycin A1 Chemical Structure

CAS No. : 642-15-9

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Description

Antimycin A1 is a specific electron transfer inhibitor of ubiquinol-cytochrome c oxidoreductase. Antimycin A1 inhibits angiogenesis through decrease in VEGF production caused by inhibition of HIF-1α activation[1][2].

In Vitro

Antimycin A, a mixture of Antimycins A1, A2, A3, and A4, is an antibiotic produced by Streptomyces species and displays antifungal, insecticidal, nematocidal, and piscicidal properties[3]. Antimycin A inhibits Bcl-2 and Bcl-xL proteins, inducing apoptosis[4].

Molecular Weight

548.63

Formula

C₂₈H₄₀N₂O₉

CAS No.

642-15-9

SMILES

CC(C)CC(O[[email protected]]([[email protected]]1CCCCCC)[[email protected]](C)OC([[email protected]@H](NC(C2=CC=CC(NC=O)=C2O)=O)[[email protected]@H](C)OC1=O)=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Antimycin A1Antimycin A 1Antimycin A-1Mitochondrial Metabolismmitochondrialbc1complexelectrontransferBcl-xLBcl-2Inhibitorinhibitorinhibit

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Antimycin A1
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