1. Metabolic Enzyme/Protease
    Apoptosis
  2. Mitochondrial Metabolism
    Apoptosis
  3. Antimycin A3

Antimycin A3 

Cat. No.: HY-105755 Purity: >98.0%
Handling Instructions

Antimycin A3, an antibiotic isolated from a number of Streptomyces species, shows antifungal activities. Antimycin A3 is a potent inhibitor of respiration. Antimycin A3 inhibits the electron transfer activity of ubiquinol-cytochrome c oxidoreductase. Antimycin A3 inhibits ATP-citrate lyase with a Ki value of 60.1 µM.

For research use only. We do not sell to patients.

Antimycin A3 Chemical Structure

Antimycin A3 Chemical Structure

CAS No. : 522-70-3

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1 mg USD 730 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Antimycin A3, an antibiotic isolated from a number of Streptomyces species, shows antifungal activities. Antimycin A3 is a potent inhibitor of respiration. Antimycin A3 inhibits the electron transfer activity of ubiquinol-cytochrome c oxidoreductase. Antimycin A3 inhibits ATP-citrate lyase with a Ki value of 60.1 µM[1][2][3].

In Vitro

Antimycin A3 induces apoptosis of cancer cells by selectively killing cancer cells that expressed high levels of anti-apoptotic Bcl-2 and Bcl-XL[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

520.58

Formula

C₂₆H₃₆N₂O₉

CAS No.

522-70-3

SMILES

CC(C)CC(O[[email protected]]([[email protected]]1CCCC)[[email protected]](C)OC([[email protected]@H](NC(C2=CC=CC(NC=O)=C2O)=O)[[email protected]@H](C)OC1=O)=O)=O.CCC(C)C(O[[email protected]]([[email protected]]3CCCC)[[email protected]](C)OC([[email protected]@H](NC(C4=CC=CC(NC=O)=C4O)=O)[[email protected]@H](C)OC3=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
References

Purity: >98.0%

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Keywords:

Antimycin A3Antimycin A 3Antimycin A-3Mitochondrial MetabolismApoptosisInhibitorinhibitorinhibit

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Antimycin A3
Cat. No.:
HY-105755
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