1. Autophagy NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  2. Autophagy Reactive Oxygen Species
  3. Antiproliferative agent-5

Antiproliferative agent-5 (compound 4o) can significantly and irreversibly inhibit proliferation of gastric cancer cells. Antiproliferative agent-5 causes the G2/M phase arrest, and induces ROS accumulation and activation of autophagy. Antiproliferative agent-5 can be used for researching anticancer.

For research use only. We do not sell to patients.

Antiproliferative agent-5 Chemical Structure

Antiproliferative agent-5 Chemical Structure

CAS No. : 2459892-41-0

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Description

Antiproliferative agent-5 (compound 4o) can significantly and irreversibly inhibit proliferation of gastric cancer cells. Antiproliferative agent-5 causes the G2/M phase arrest, and induces ROS accumulation and activation of autophagy. Antiproliferative agent-5 can be used for researching anticancer[1].

IC50 & Target

ROS, Autophagy[1]

Molecular Weight

597.49

Formula

C28H21BrN8OS

CAS No.
SMILES

O=C(C1=CC=C(NC2=CC(C)=NC3=NC(SCC4=NC5=CC=CC=C5N4)=NN23)C=C1)/C=C/C6=NC(Br)=CC=C6

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Room temperature in continental US; may vary elsewhere.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Antiproliferative agent-5
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HY-146390
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