2. PROTAC
  3. PROTAC Linkers
  4. BDP FL-PEG5-propargyl

BDP FL-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

BDP FL-PEG5-propargyl Chemical Structure

BDP FL-PEG5-propargyl Chemical Structure

CAS No. : 2093197-93-2

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1 mg USD 110 In-stock
5 mg USD 310 In-stock
10 mg USD 500 In-stock
25 mg USD 950 In-stock
50 mg USD 1550 In-stock
100 mg USD 2450 In-stock
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Based on 1 publication(s) in Google Scholar

BDP FL-PEG5-propargyl Related Antibodies

Top Publications Citing Use of Products

View All PROTAC Linkers Isoform Specific Products:

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

  • Biological Activity

  • Purity & Documentation

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Description

BDP FL-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

BDP FL-PEG5-propargyl Related Antibodies
Molecular Weight

571.04

Formula

C27H38B3F2N3O62-
CAS No.
Appearance

Oil

Color

Brown to black

SMILES

O=C(NCCOCCOCCOCCOCCOCC#C)CCC1=CC=C(C=C(C(C)=C2)[N]3=C2C)[N-]1B3([F-])([F-])=B[B+]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (175.12 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7512 mL 8.7560 mL 17.5119 mL
5 mM 0.3502 mL 1.7512 mL 3.5024 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7512 mL 8.7560 mL 17.5119 mL 43.7798 mL
5 mM 0.3502 mL 1.7512 mL 3.5024 mL 8.7560 mL
10 mM 0.1751 mL 0.8756 mL 1.7512 mL 4.3780 mL
15 mM 0.1167 mL 0.5837 mL 1.1675 mL 2.9187 mL
20 mM 0.0876 mL 0.4378 mL 0.8756 mL 2.1890 mL
25 mM 0.0700 mL 0.3502 mL 0.7005 mL 1.7512 mL
30 mM 0.0584 mL 0.2919 mL 0.5837 mL 1.4593 mL
40 mM 0.0438 mL 0.2189 mL 0.4378 mL 1.0945 mL
50 mM 0.0350 mL 0.1751 mL 0.3502 mL 0.8756 mL
60 mM 0.0292 mL 0.1459 mL 0.2919 mL 0.7297 mL
80 mM 0.0219 mL 0.1094 mL 0.2189 mL 0.5472 mL
100 mM 0.0175 mL 0.0876 mL 0.1751 mL 0.4378 mL
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BDP FL-PEG5-propargyl Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BDP FL-PEG5-propargyl2093197-93-2PROTAC LinkersInhibitorinhibitorinhibit

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