1. Immunology/Inflammation
  2. NO Synthase
  3. Carboxyebselen

Carboxyebselen (Synonyms: HOOC-Ebs)

Cat. No.: HY-139448
Handling Instructions

Carboxyebselen (HOOC-Ebs) is a potent and selective inhibitor of endothelial nitric oxide synthase (eNOS).

For research use only. We do not sell to patients.

Carboxyebselen Chemical Structure

Carboxyebselen Chemical Structure

CAS No. : 153871-75-1

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Description

Carboxyebselen (HOOC-Ebs) is a potent and selective inhibitor of endothelial nitric oxide synthase (eNOS)[1].

In Vivo

Carboxyebselen (HOOC-Ebs), a derivative of Ebselen (Ebs) inhibits NOS present in enzymatic preparations from bovine endothelium, porcine cerebella, and murine spleen, however, it is both more potent and more selective for the constitutive endothelial NOS than Ebs. Unlike Ebs, HOOC-Ebs (0.1-30 microM) causes a concentration-dependent endothelium-independent relaxations of rings of rabbit aorta[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

318.19

Formula

C₁₄H₉NO₃Se

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Carboxyebselen
Cat. No.:
HY-139448
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