1. Cell Cycle/DNA Damage
    PROTAC
  2. CDK
    Ligand for Target Protein for PROTAC
  3. LSN3106729

LSN3106729 

Cat. No.: HY-126534
Handling Instructions

LSN3106729, the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. LSN3106729 and a CRBN ligand have been used to design PROTAC CDK4/6 degrader.

For research use only. We do not sell to patients.

LSN3106729 Chemical Structure

LSN3106729 Chemical Structure

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Description

LSN3106729, the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. LSN3106729 and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1].

Molecular Weight

494.54

Formula

C₂₅H₂₈F₂N₈O

SMILES

FC(C=N1)=C(C2=CC(N(C(C)C)C(CO)=N3)=C3C(F)=C2)N=C1NC4=NC=C(C=C4)CN5CCNCC5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

LSN3106729LSN 3106729LSN-3106729CDKLigand for Target Protein for PROTACCyclin dependent kinaseTarget Protein-binding MoietyligandantitumorCRBNdegraderPROTACInhibitorinhibitorinhibit

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Product Name:
LSN3106729
Cat. No.:
HY-126534
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