1. Anti-infection
  2. Bacterial Antibiotic
  3. Ceftaroline fosamil (inner)

Ceftaroline fosamil (inner)  (Synonyms: TAK-599 free acid; PPI0903 free acid)

Cat. No.: HY-14738
Handling Instructions

Ceftaroline fosamil (inner) (TAK-599 free acid), a cephalosporin derivative, is an N-phosphono proagent of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil (inner) can be used for the research of MRSA infection.

For research use only. We do not sell to patients.

Ceftaroline fosamil (inner) Chemical Structure

Ceftaroline fosamil (inner) Chemical Structure

CAS No. : 229016-73-3

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Description

Ceftaroline fosamil (inner) (TAK-599 free acid), a cephalosporin derivative, is an N-phosphono proagent of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil (inner) can be used for the research of MRSA infection[1][2][3].

IC50 & Target

β-lactam

 

In Vivo

Ceftaroline fosamil inner salt (s.c.) shows protective effects against experimental systemic infection caused by S. aureus N133 in mice, with ED50s of 1.60-2.37 mg/kg[1].
Ceftaroline fosamil inner salt (10 mg/kg; s.c.) disappeares rapidly and converts smoothly into T-91825 in blood of rats and monkeys[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

684.68

Formula

C22H21N8O8PS4

CAS No.
SMILES

O=C1[C@@H](NC(/C(C2=NSC(NP(O)(O)=O)=N2)=N\OCC)=O)[C@@]3([H])SCC(SC4=NC(C5=CC=[N+](C)C=C5)=CS4)=C(C([O-])=O)N13

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Ceftaroline fosamil (inner) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ceftaroline fosamil (inner)
Cat. No.:
HY-14738
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