1. Cell Cycle/DNA Damage
  2. Cyclin G-associated Kinase (GAK)
  3. Culmerciclib

Culmerciclib is a cyclin dependent kinase (CDK) inhibitor, and has antineoplastic activity.

For research use only. We do not sell to patients.

Culmerciclib Chemical Structure

Culmerciclib Chemical Structure

CAS No. : 2004705-28-4

Size Price Stock Quantity
5 mg USD 215 In-stock
10 mg USD 350 In-stock
25 mg USD 700 In-stock
50 mg USD 1120 In-stock
100 mg USD 1800 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Culmerciclib is a cyclin dependent kinase (CDK) inhibitor, and has antineoplastic activity[1].

Molecular Weight

446.52

Formula

C24H27FN8

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

FC1=C(C2=CC3=C(C(C)C)N(C)N=C3C=C2)N=C(NC4=NC=C(N5CCNCC5)C=C4)N=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 2 mg/mL (4.48 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2395 mL 11.1977 mL 22.3954 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2395 mL 11.1977 mL 22.3954 mL 55.9885 mL
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Culmerciclib Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Culmerciclib
Cat. No.:
HY-147258
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