2. GPCR/G Protein
    Neuronal Signaling
  3. Dopamine Receptor
  4. CY 208-243

CY 208-243 

Cat. No.: HY-106094 Purity: 99.98%
COA Handling Instructions

CY 208-243 is a selective dopamine D1 receptor agonist which exhibits antiparkinsonian activity.

For research use only. We do not sell to patients.

CY 208-243 Chemical Structure

CY 208-243 Chemical Structure

CAS No. : 100999-26-6

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 438 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 438 In-stock
Solid
1 mg USD 145 In-stock
5 mg USD 285 In-stock
10 mg USD 485 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

CY 208-243 is a selective dopamine D1 receptor agonist which exhibits antiparkinsonian activity[1].

IC50 & Target

D1 Receptor

 

In Vivo

Pretreatment with CY 208-243 (2.5 mg/kg; s.c.) prevents the increase of DA release and metabolism induced by the D-1 antagonist, SCH 23390 (0.05 mg/kg; s.c.)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats (180-200 g)[1]
Dosage: 2.5 mg/kg
Administration: Subcutaneous
Result: Prevented the increase of DA release and metabolism induced by the D-1 antagonist.
Molecular Weight

274.36

Appearance

Solid

Formula

C19H18N2
CAS No.
SMILES

CN1[[email protected]@](C2)([H])[[email protected]@](C3=CC=CC=C3C1)([H])C4=CC=CC5=C4C2=CN5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (182.24 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6448 mL 18.2242 mL 36.4485 mL
5 mM 0.7290 mL 3.6448 mL 7.2897 mL
10 mM 0.3645 mL 1.8224 mL 3.6448 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: 99.98%

COA (250 KB) LCMS (260 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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C1   V1   C2   V2

Keywords:

CY 208-243100999-26-6Dopamine ReceptorDopamineD1Inhibitorinhibitorinhibit

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