1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. DBCO-PEG4-GGFG-DX8951

DBCO-PEG4-GGFG-DX8951 

Cat. No.: HY-134723
Handling Instructions

DBCO-PEG4-GGFG-DX8951 is a drug-linker conjugate for ADC with potent antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the non-cleavable ADC linker DBCO-PEG4-GGFG.

For research use only. We do not sell to patients.

DBCO-PEG4-GGFG-DX8951 Chemical Structure

DBCO-PEG4-GGFG-DX8951 Chemical Structure

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Description

DBCO-PEG4-GGFG-DX8951 is a drug-linker conjugate for ADC with potent antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the non-cleavable ADC linker DBCO-PEG4-GGFG[1].

IC50 & Target[1]

Traditional Cytotoxic Agents

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linke[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1375.45

Formula

C₇₂H₇₉FN₁₀O₁₇

SMILES

O=C1OCC2=C(C=C(C3=NC4=CC(F)=C(C)C(CC[[email protected]@H]5NC(COCNC(CNC([[email protected]](CC6=CC=CC=C6)NC(CNC(CNC(CCOCCOCCOCCOCCNC(CCC(N7C8=CC=CC=C8C#CC9=CC=CC=C9C7)=O)=O)=O)=O)=O)=O)=O)=O)=C4C5=C3C%10)N%10C2=O)[[email protected]]1(CC)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

DBCO-PEG4-GGFG-DX8951Drug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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Product Name:
DBCO-PEG4-GGFG-DX8951
Cat. No.:
HY-134723
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