1. NF-κB
    Apoptosis
    Immunology/Inflammation
  2. NF-κB
    TNF Receptor
    Interleukin Related
  3. Dexanabinol

Dexanabinol (Synonyms: HU-211)

Cat. No.: HY-106387 Purity: 98.17%
Handling Instructions

Dexanabinol (HU-211) is an artificially synthesized cannabinoid derivative and lacks cannabimimetic effects. Dexanabinol exhibits not only the antioxidant and neuroprotective activities in brain but also anti-inflammatory activity by inhibiting NF-κB and decreasing cytokines such as TNFα and interleukin-6, which could ensure the integrity of BBB and reduce cell apoptosis and death. Dexanabinol is widely used in head injury or stroke treatment and has been shown to be safe in animals and humans.

For research use only. We do not sell to patients.

Dexanabinol Chemical Structure

Dexanabinol Chemical Structure

CAS No. : 112924-45-5

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Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Dexanabinol (HU-211) is an artificially synthesized cannabinoid derivative and lacks cannabimimetic effects. Dexanabinol exhibits not only the antioxidant and neuroprotective activities in brain but also anti-inflammatory activity by inhibiting NF-κB and decreasing cytokines such as TNFα and interleukin-6, which could ensure the integrity of BBB and reduce cell apoptosis and death. Dexanabinol is widely used in head injury or stroke treatment and has been shown to be safe in animals and humans[1].

IC50 & Target[1]

NF-κB

 

TNFα

 

IL-6

 

Molecular Weight

386.57

Formula

C₂₅H₃₈O₃

CAS No.

112924-45-5

SMILES

OC1=C2[[email protected]]3([H])[[email protected]@](CC=C(CO)C3)([H])C(C)(C)OC2=CC(C(C)(C)CCCCCC)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
References
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Keywords:

DexanabinolHU-211HU211HU 211NF-κBTNF ReceptorInterleukin RelatedNuclear factor-κBNuclear factor-kappaBTumor Necrosis Factor ReceptorTNFRILInhibitorinhibitorinhibit

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Dexanabinol
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