1. Isotope-Labeled Compounds
  2. Carbon-13 (13C)
    Deuterium (2H, D)
  3. Doxorubicin-13C,d3

Doxorubicin-13C,d3 (Synonyms: Hydroxydaunorubicin-13C,d3)

Cat. No.: HY-15142AS
Handling Instructions

Doxorubicin-13C,d3 is the deuterium and 13C labeled Doxorubicin. Doxorubicin (Hydroxydaunorubicin), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DN

For research use only. We do not sell to patients.

Doxorubicin-13C,d3 Chemical Structure

Doxorubicin-13C,d3 Chemical Structure

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Description

Doxorubicin-13C,d3 is the deuterium and 13C labeled Doxorubicin. Doxorubicin (Hydroxydaunorubicin), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DN

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

547.53

Formula

C2613CH26D3NO11

SMILES

OC1=C(C(C2=CC=CC(O[13C]([2H])([2H])[2H])=C2C3=O)=O)C3=C(O)C4=C1C[[email protected]](C(CO)=O)(O)C[[email protected]@H]4O[[email protected]]5C[[email protected]@H]([[email protected]@H]([[email protected]@H](O5)C)O)N

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Product Name:
Doxorubicin-13C,d3
Cat. No.:
HY-15142AS
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