1. Cell Cycle/DNA Damage
  2. Deubiquitinase
  3. DUBs-IN-3

DUBs-IN-3 

Cat. No.: HY-50737 Purity: 99.00%
Handling Instructions

DUBs-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c with an IC50 of 0.56 μM for USP8.

For research use only. We do not sell to patients.

DUBs-IN-3 Chemical Structure

DUBs-IN-3 Chemical Structure

CAS No. : 924296-17-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 462 In-stock
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2520 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of DUBs-IN-3:

Top Publications Citing Use of Products

    DUBs-IN-3 purchased from MCE. Usage Cited in: J Invest Dermatol. 2019 Nov 6. pii: S0022-202X(19)33384-6.

    Western blot analysis of SCCRDEB4 cells treated with the USP8 inhibitor DUBs-IN-3 for 24 hours.
    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    DUBs-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c with an IC50 of 0.56 μM for USP8.

    IC50 & Target

    IC50: 0.56 μM (USP8)[1]

    Molecular Weight

    287.28

    Formula

    C₁₆H₉N₅O

    CAS No.

    924296-17-3

    SMILES

    C=CCO/N=C1C2=C(N=C(C#N)C(C#N)=N2)C3=CC=CC=C/13

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : 20.1 mg/mL (69.97 mM; Need ultrasonic and warming)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 3.4809 mL 17.4046 mL 34.8092 mL
    5 mM 0.6962 mL 3.4809 mL 6.9618 mL
    10 mM 0.3481 mL 1.7405 mL 3.4809 mL
    *Please refer to the solubility information to select the appropriate solvent.
    References
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    The molarity calculator equation

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    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2

    Keywords:

    DUBs-IN-3DeubiquitinaseDUBsInhibitorinhibitorinhibit

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    Product name:
    DUBs-IN-3
    Cat. No.:
    HY-50737
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