2. Metabolic Enzyme/Protease
  3. SGK
  4. EMD638683 R-Form

EMD638683 R-Form 

Cat. No.: HY-15193A Purity: 99.68%
COA Handling Instructions

EMD638683 R-Form is the R-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM.

For research use only. We do not sell to patients.

EMD638683 R-Form Chemical Structure

EMD638683 R-Form Chemical Structure

CAS No. : 1184940-47-3

Size Price Stock Quantity
Free Sample (0.1 - 0.5 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 436 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 436 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 396 In-stock
Estimated Time of Arrival: December 31
10 mg USD 594 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1320 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2112 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of EMD638683 R-Form:

Top Publications Citing Use of Products

2 Publications Citing Use of MCE EMD638683 R-Form

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

EMD638683 R-Form is the R-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM.

IC50 & Target

SGK1[1]
Molecular Weight

364.34

Appearance

Solid

Formula

C18H18F2N2O4
CAS No.
SMILES

CC1=C(CC)C(C(NNC([[email protected]](O)C2=CC(F)=CC(F)=C2)=O)=O)=CC=C1O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 66.67 mg/mL (182.99 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7447 mL 13.7234 mL 27.4469 mL
5 mM 0.5489 mL 2.7447 mL 5.4894 mL
10 mM 0.2745 mL 1.3723 mL 2.7447 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 3.33 mg/mL (9.14 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 3.33 mg/mL (9.14 mM); Clear solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: 3.33 mg/mL (9.14 mM); Clear solution; Need ultrasonic

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.68%

COA (246 KB) HNMR (206 KB) LCMS (122 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

EMD638683 R-Form1184940-47-3SGKSerum-glucocorticoid regulated kinaseSerum and glucocorticoid-regulated kinaseInhibitorinhibitorinhibit

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