2. Vitamin D Related/Nuclear Receptor
    Autophagy
  3. Androgen Receptor
    Autophagy
  4. Deutenzalutamide-d3

Deutenzalutamide-d3  (Synonyms: Enzalutamide-d3; MDV3100-d3)

Cat. No.: HY-70002S Purity: 99.81%
COA Handling Instructions

Deutenzalutamide-d3-d3 is a deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells[1].

For research use only. We do not sell to patients.

Deutenzalutamide-d<sub>3</sub> Chemical Structure

Deutenzalutamide-d3 Chemical Structure

CAS No. : 1443331-82-5

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1 mg USD 300 In-stock
Estimated Time of Arrival: December 31
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10 mg USD 1440 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Deutenzalutamide-d3-d3 is a deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells[1].

Molecular Weight

467.45

Appearance

Solid

Formula

C21H13D3F4N4O2S
CAS No.
SMILES

O=C(NC([2H])([2H])[2H])C1=CC=C(N(C(N2C3=CC=C(C#N)C(C(F)(F)F)=C3)=S)C(C)(C)C2=O)C=C1F
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (53.48 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1393 mL 10.6963 mL 21.3927 mL
5 mM 0.4279 mL 2.1393 mL 4.2785 mL
10 mM 0.2139 mL 1.0696 mL 2.1393 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Keywords:

Deutenzalutamide-d31443331-82-5Enzalutamide-d3MDV3100-d3Androgen ReceptorAutophagydeuteriumcancerLNCaPprostatecellsInhibitorinhibitorinhibit

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