1. Membrane Transporter/Ion Channel
  2. P-glycoprotein
  3. Epoxylathyrol

Epoxylathyrol 

Cat. No.: HY-N0425
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Epoxylathyrol, an epoxylathyrane derivative isolated from the Euphorbia boetica, is a P-glycoprotein (P-gp) inhibitor. Epoxylathyrol is a P-gp-mediated multidrug resistance (MDR) reverser.

For research use only. We do not sell to patients.

Epoxylathyrol Chemical Structure

Epoxylathyrol Chemical Structure

CAS No. : 28649-60-7

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Description

Epoxylathyrol, an epoxylathyrane derivative isolated from the Euphorbia boetica, is a P-glycoprotein (P-gp) inhibitor. Epoxylathyrol is a P-gp-mediated multidrug resistance (MDR) reverser[1][2].

In Vitro

Epoxylathyrol has no significant antiproliferative activity in EPG85-257P (parental; IC50>100 uM), EPG85-257RNOV (multidrug resistance [MDR] phenotype; IC50>100 uM), and EPG85-257RDB (multidrug resistance [MDR] phenotype; IC50=70.53 uM)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

350.45

Formula

C₂₀H₃₀O₅

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

EpoxylathyrolP-glycoproteinP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243Inhibitorinhibitorinhibit

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Epoxylathyrol
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HY-N0425
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