2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. ERRγ agonist-1

ERRγ agonist-1 is a potent ERRγ agonist. ERRγ agonist-1 increases transcriptional activities of ERRγ. ERRγ agonist-1 has the potential for the research of neuropsychological disorders.

For research use only. We do not sell to patients.

ERRγ agonist-1 Chemical Structure

ERRγ agonist-1 Chemical Structure

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 272 In-stock
Solution
10 mM * 1 mL in DMSO USD 272 In-stock
Solid
5 mg USD 248 In-stock
10 mg USD 398 In-stock
25 mg USD 796 In-stock
50 mg USD 1270 In-stock
100 mg USD 2030 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

ERRγ agonist-1 Related Antibodies

Top Publications Citing Use of Products

View All Estrogen Receptor/ERR Isoform Specific Products:

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

  • Biological Activity

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Description

ERRγ agonist-1 is a potent ERRγ agonist. ERRγ agonist-1 increases transcriptional activities of ERRγ. ERRγ agonist-1 has the potential for the research of neuropsychological disorders[1].

IC50 & Target

ERRγ

 

In Vitro

ERRγ agonist-1 (compound 5d) (5 µM; 3 days) significantly increases the expression of tyrosine hydroxylase (TH) and dopamine transporter (DAT), DAergic neuronal phenotypes (dopaminergic neuronal phenotype) in neuroblastoma SH-SY5Y cells[1].
ERRγ agonist-1 (5 µM; 3 days) induces DAergic neuronal phenotypes via the ERRγ-mediated up-regulation of CREB-signaling pathway[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ERRγ agonist-1 Related Antibodies

Western Blot Analysis[1]

Cell Line: SH-SY5Y cells
Concentration: 5 µM
Incubation Time: 3 days
Result: Increased the DAergic neuronal-specific markers, TH and DAT in neuroblastoma SH-SY5Y cells.
Molecular Weight

311.38

Formula

C17H21N5O
Appearance

Solid

Color

Light yellow to yellow

SMILES

CCCN(C1=CC=C(C=C1)/C=N/NC(C2=CC=C(N=C2)N)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (80.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2115 mL 16.0576 mL 32.1151 mL
5 mM 0.6423 mL 3.2115 mL 6.4230 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2115 mL 16.0576 mL 32.1151 mL 80.2878 mL
5 mM 0.6423 mL 3.2115 mL 6.4230 mL 16.0576 mL
10 mM 0.3212 mL 1.6058 mL 3.2115 mL 8.0288 mL
15 mM 0.2141 mL 1.0705 mL 2.1410 mL 5.3525 mL
20 mM 0.1606 mL 0.8029 mL 1.6058 mL 4.0144 mL
25 mM 0.1285 mL 0.6423 mL 1.2846 mL 3.2115 mL
30 mM 0.1071 mL 0.5353 mL 1.0705 mL 2.6763 mL
40 mM 0.0803 mL 0.4014 mL 0.8029 mL 2.0072 mL
50 mM 0.0642 mL 0.3212 mL 0.6423 mL 1.6058 mL
60 mM 0.0535 mL 0.2676 mL 0.5353 mL 1.3381 mL
80 mM 0.0401 mL 0.2007 mL 0.4014 mL 1.0036 mL
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ERRγ agonist-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ERRγ agonist-1ERRγ agonist1ERRγ agonist 1Estrogen Receptor/ERRdopaminergic neuronal phenotypeneuropsychological disordersCREB-signaling pathwaySH-SY5Y cellsTHDATInhibitorinhibitorinhibit

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