Ga(III) protoporphyrin IX 

Ga(III)protoporphyrin-IX is a model for the key interporphyrin interactions in malaria pigment. Ga(III)protoporphyrin-IX acts as a potent antibacterial against gram-negative, gram-positive, and acid-fast bacteria. Ga(III)protoporphyrin-IX is readily soluble in methanol (MeOH). Ga(III)protoporphyrin IX are as malarial pigment analogues for agent development and as potential antibacterial agents^[1].

Ga(III)protoporphyrin-IX has also been shown to bind to heme containing proteins and enzymes when it is included in the cellular growth medium of the Grampositive bacteria Enterococcus faecalis which does not depend on heme for cell growth. Ga(III)protoporphyrin-IX has shown to be a suitable mimic of heme and has potential applications in heme replacement/substitution^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

629.36

C₃₄H₃₁GaN₄O₄

222556-71-0

[O-]C(CCC(C1=CC(C(CCC([O-])=O)=C2C)=[N](C2=C3)[Ga+3]4([N-]5C3=C6C)[N-]1C7=CC(C(C=C)=C8C)=[N]4C8=CC5=C6C=C)=C7C)=O.[H+]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Pinter TB, et al. Spectroscopic and theoretical studies of Ga(III)protoporphyrin-IX and its reactions with myoglobin. Inorg Chem. 2012;51(6):3743-3753.  [Content Brief]