1. GPCR/G Protein
    Neuronal Signaling
  2. Sigma Receptor
  3. Glycerol phenylbutyrate-D15

Glycerol phenylbutyrate-D15 (Synonyms: HPN-100-D15)

Cat. No.: HY-B2087S
Handling Instructions

Glycerol phenylbutyrate-D15 is a deuterium labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pKi of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger drug.

For research use only. We do not sell to patients.

Glycerol phenylbutyrate-D15 Chemical Structure

Glycerol phenylbutyrate-D15 Chemical Structure

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Description

Glycerol phenylbutyrate-D15 is a deuterium labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pKi of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger drug[1][2].

IC50 & Target

σ2 receptor[1].

In Vivo

Glycerol phenylbutyrate (GPB) has the potential for the treatment of hyperammonemia. Glycerol phenylbutyrate (GPB) may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders[1][2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

545.74

Formula

C₃₃H₂₃D₁₅O₆

SMILES

O=C(OCC(OC(CCCC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O)COC(CCCC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=O)CCCC3=C([2H])C([2H])=C([2H])C([2H])=C3[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Glycerol phenylbutyrate-D15HPN-100-D15Sigma ReceptorInhibitorinhibitorinhibit

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Glycerol phenylbutyrate-D15
Cat. No.:
HY-B2087S
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