1. Neuronal Signaling
  2. Amyloid-β
  3. GV-971

GV-971 (Synonyms: Sodium Oligo-mannurarate)

Cat. No.: HY-130263
Handling Instructions

GV-971 is a potent anti-Alzheimer’s disease agent, which suppresses gut dysbiosis and the associated phenylalanine/isoleucine accumulation, harnesses neuroinflammation and reverses the cognition impairment. GV-97 penetrates the blood-brain-barrier, directly binds to multiple subregions of to inhibit Aβ fibril formation, and reduces the Aβ plaque deposition, and tau phosphorylation.

For research use only. We do not sell to patients.

GV-971 Chemical Structure

GV-971 Chemical Structure

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Description

GV-971 is a potent anti-Alzheimer’s disease agent, which suppresses gut dysbiosis and the associated phenylalanine/isoleucine accumulation, harnesses neuroinflammation and reverses the cognition impairment. GV-97 penetrates the blood-brain-barrier, directly binds to multiple subregions of to inhibit Aβ fibril formation, and reduces the Aβ plaque deposition, and tau phosphorylation[1].

IC50 & Target

Amyloid-β[1]

SMILES

O[[email protected]]1[[email protected]](O[H])[[email protected]@H](C(O[Na])=O)O[[email protected]@H](OC(C(C(O[Na])=O)O)C(C(O[Na])=O)O)[[email protected]]1O.[n].[m].[m'].[n=1-9; m=0,1 or 2; m'=0 or 1]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

GV-971Sodium Oligo-mannurarateGV971GV 971Amyloid-ββ-amyloid peptideAbetaInhibitorinhibitorinhibit

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GV-971
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HY-130263
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