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LCL-ER(dec) 

Cat. No.: HY-132982
Handling Instructions

LCL-ER(dec) is a potent and selective oligonucleotide-type degrader via targeting transcription factor (TFs). The main target of LCL-ER(dec) is SNIPER (specific and non-genetic inhibitor of apoptosis protein [IAP]-dependent protein erasers). LCL-ER(dec) selectively degrades ERα (estrogen receptor α) via the UPS (ubiquitin-proteasome system). LCL-ER(dec) is applicable to the development of other oligonucleotide-type degraders that target different TFs.

For research use only. We do not sell to patients.

LCL-ER(dec) Chemical Structure

LCL-ER(dec) Chemical Structure

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Description

LCL-ER(dec) is a potent and selective oligonucleotide-type degrader via targeting transcription factor (TFs). The main target of LCL-ER(dec) is SNIPER (specific and non-genetic inhibitor of apoptosis protein [IAP]-dependent protein erasers). LCL-ER(dec) selectively degrades ERα (estrogen receptor α) via the UPS (ubiquitin-proteasome system). LCL-ER(dec) is applicable to the development of other oligonucleotide-type degraders that target different TFs[1].

IC50 & Target

ERα[1]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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LCL-ER(dec)
Cat. No.:
HY-132982
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